Atypical teratoid/rhabdoid tumour with leptomeningeal dissemination in an adult
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A 22-year-old man presented with a rare case of atypical teratoid/rhabdoid tumour (AT/RT). Magnetic resonance imaging showed a left cerebellar mass with leptomeningeal dissemination. Partial resection was performed. Histological examination revealed AT/RT. Postoperatively, whole neuraxis and local irradiation were performed. Three-drug chemotherapy with ifosfamide, cisplatin, and etoposide, and adjuvant intrathecal administration of methotrexate were repeated. Near complete response was achieved, and no tumour recurrence/progression has been noticed during the follow up of 24 months. Intensive radiochemotherapy can successfully control AT/RT, even with leptomeningeal dissemination.
- Atypical teratoid/rhabdoid tumour with leptomeningeal dissemination in an adult
Volume 146, Issue 9 , pp 1033-1038
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- Keywords: Atypical teratoid/rhabdoid tumour; chemotherapy; leptomeningeal dissemination; radiation.
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