Microchimica Acta

, Volume 174, Issue 3, pp 231–238

Surface activation of plasma-patterned carbon nanotube based DNA sensing electrodes

  • Eun Jin Park
  • Joon-Hyung Jin
  • Joon Hyub Kim
  • Nam Ki Min
Original Paper

DOI: 10.1007/s00604-011-0605-4

Cite this article as:
Park, E.J., Jin, JH., Kim, J.H. et al. Microchim Acta (2011) 174: 231. doi:10.1007/s00604-011-0605-4

Abstract

We have studied the effect of treatment of multiwalled carbon nanotubes (MWCNTs) for use in DNA-based biosensors with oxygen plasma. Well-patterned MWCNT electrodes were photolithographically fabricated on glass substrates. Pure oxygen was used for etching and functionalization of the MWCNT film in a lab-made plasma chamber. The resulting electrodes exhibited a dramatic change in the morphology of their surface, the chemical composition, and the electrochemical properties in terms of peak current and peak potential separation. The electrodes also showed increased DNA immobilization efficiency and much higher sensitivity in the detection of target DNA as compared to non-treated MWCNT electrodes. Plasma treatment was optimized and electrodes were characterized by atomic force microscopy, X-ray photoelectron spectroscopy, cyclic voltammetry, and differential pulse voltammetry.

Figure

Well-patterned MWCNT electrodes were photolithographically fabricated on glass substrates. Pure oxygen was used for etching and functionalization of the MWCNT film. The electrodes showed increased DNA immobilization efficiency and much higher sensitivity in the detection of target DNA as compared to non-treated MWCNT electrodes

Keywords

MWCNT O2 plasma treatment Electrochemical analysis DNA sensor 

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Eun Jin Park
    • 1
  • Joon-Hyung Jin
    • 1
  • Joon Hyub Kim
    • 1
  • Nam Ki Min
    • 1
  1. 1.Department of Biomicrosystem TechnologyKorea UniversitySeoulKorea

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