Microchimica Acta

, Volume 174, Issue 1, pp 41–46

Enhanced conductivity of a glassy carbon electrode modified with a graphene-doped film of layered double hydroxides for selectively sensing of dopamine

Authors

    • Key Laboratory of Chemo − Biosensing, Anhui Province; College of Chemistry and Materials ScienceAnhui Normal University
  • Wei Peng
    • Key Laboratory of Chemo − Biosensing, Anhui Province; College of Chemistry and Materials ScienceAnhui Normal University
  • Lin Liu
    • Key Laboratory of Chemo − Biosensing, Anhui Province; College of Chemistry and Materials ScienceAnhui Normal University
  • Min Tang
    • Key Laboratory of Chemo − Biosensing, Anhui Province; College of Chemistry and Materials ScienceAnhui Normal University
  • Feng Gao
    • Key Laboratory of Chemo − Biosensing, Anhui Province; College of Chemistry and Materials ScienceAnhui Normal University
    • Key Laboratory of Chemo − Biosensing, Anhui Province; College of Chemistry and Materials ScienceAnhui Normal University
Original Paper

DOI: 10.1007/s00604-011-0593-4

Cite this article as:
Wang, Y., Peng, W., Liu, L. et al. Microchim Acta (2011) 174: 41. doi:10.1007/s00604-011-0593-4

Abstract

A strategy is presented for doping graphene into layered double hydroxide films (LDHs) as a means of improving charge transport of the LDH film in a modified glassy carbon electrode. This result in an enhanced electrocatalytic current for dopamine (DA) and a good separation of the potentials of DA, uric acid and ascorbic acid. Under selected conditions, the square wave voltammetric response of the electrode to DA is linear in the concentration range from 1.0 to 199 μM even in the presence of 0.1 mM ascorbic acid, and the detection limit is 0.3 μM at a signal-to-noise ratio of 3. The method was applied to the determination of DA in pharmaceutical injections with satisfactory results.

https://static-content.springer.com/image/art%3A10.1007%2Fs00604-011-0593-4/MediaObjects/604_2011_593_Figa_HTML.gif
Figure

A strategy is presented for doping graphene into layered double hydroxide films (LDHs) as a means of improving charge transport of the LDH film in a modified glassy carbon electrode. This result in an enhanced electrocatalytic current for dopamine (DA) and the square wave voltammetric response of the electrode to DA is linear in the concentration range from 1.0 to 199 μM with the detection limit of 0.3 μM. The method was applied to the determination of DA in pharmaceutical injections with satisfactory results.

Keywords

Layered double hydroxidesGrapheneDopamineModified electrodeComposite film

Copyright information

© Springer-Verlag 2011