Surgery Today

, Volume 41, Issue 8, pp 1145–1149

Stromal sarcoma of the breast with lung metastases showing a clinical complete response to doxorubicin plus ifosfamide treatment: Report of a case

  • Aiko Sueta
  • Yutaka Yamamoto
  • Katsuhiko Inoue
  • Kazumi Kuriwaki
  • Hirotaka Iwase
Case Report

DOI: 10.1007/s00595-010-4406-x

Cite this article as:
Sueta, A., Yamamoto, Y., Inoue, K. et al. Surg Today (2011) 41: 1145. doi:10.1007/s00595-010-4406-x

Abstract

A 29-year-old woman presented with a painful right breast tumor, measuring 15 cm in diameter, which had progressed rapidly over 3 months. Core needle biopsy of the tumor revealed a malignant mesenchymal tumor. A mastectomy was performed, and pathological examination of the tumor showed stromal sarcoma. Solitary pleural dissemination in the right lung was suspected, based on the computed tomography image taken before the operation. Two months after surgery, bilateral multiple lung nodules were demonstrated. Systemic chemotherapy with doxorubicin plus ifosfamide was performed, and 3 months later the lung metastases had disappeared. Moreover, there is still no sign of recurrence at 5 months after the initiation of the chemotherapy. Breast stromal sarcoma is very rare, accounting for less than 1% of mammary neoplasms, and the treatment strategy is not well established, especially regarding chemotherapy. This case demonstrates the effectiveness of chemotherapy with doxorubicin plus ifosfamide for lung metastases from breast stromal sarcoma.

Key words

Stromal sarcoma Breast Chemotherapy 

Copyright information

© Springer 2011

Authors and Affiliations

  • Aiko Sueta
    • 1
    • 3
  • Yutaka Yamamoto
    • 3
  • Katsuhiko Inoue
    • 1
  • Kazumi Kuriwaki
    • 2
  • Hirotaka Iwase
    • 3
  1. 1.Department of General SurgeryKumamoto Rousai HospitalKumamotoJapan
  2. 2.Department of PathologyKumamoto Rousai HospitalKumamotoJapan
  3. 3.Department of Breast and Endocrine Surgery, Graduate School of Medical SciencesKumamoto UniversityKumamotoJapan