Surgery Today

, 41:881

Pigmented hepatocellular adenoma: Report of a case

  • Toshiro Masuda
  • Toru Beppu
  • Koei Ikeda
  • Takatoshi Ishiko
  • Akira Chikamoto
  • Hiromitsu Hayashi
  • Hirohisa Okabe
  • Ryu Otao
  • Hiroshi Takamori
  • Tomohiro Namimoto
  • Ken-Ichi Iyama
  • Hideo Baba
Case Report

DOI: 10.1007/s00595-010-4344-7

Cite this article as:
Masuda, T., Beppu, T., Ikeda, K. et al. Surg Today (2011) 41: 881. doi:10.1007/s00595-010-4344-7

Abstract

Hepatocellular adenoma is a rare, benign neoplasm that is related to the use of contraceptives or androgenicanabolic steroids. A 51-year-old man with no history of steroid use was found to have a liver tumor. Plain computed tomography showed a high-density tumor that was enhanced in the arterial phase, and the enhancement was prolonged in the delayed phase. Magnetic resonance imaging showed that the tumor was hyperintense on in- and opposed-phase T1-weighted gradient recalled echo images and hyperintense on T1-weighted spin echo images. A partial hepatic resection was performed. A histological examination revealed normal hepatocyte-like tumor cells, composed of abundant dark brown granules of Dubin-Johnson-like pigment, which stained positively for Masson-Fontana stain. The tumor was diagnosed to be a very rare hepatocellular adenoma with the deposition of Dubin-Johnson-like pigment.

Keywords

Hepatocellular adenomaPigmentMagnetic resonance imaging

Copyright information

© Springer 2011

Authors and Affiliations

  • Toshiro Masuda
    • 1
  • Toru Beppu
    • 1
  • Koei Ikeda
    • 3
  • Takatoshi Ishiko
    • 1
  • Akira Chikamoto
    • 1
  • Hiromitsu Hayashi
    • 1
  • Hirohisa Okabe
    • 1
  • Ryu Otao
    • 1
  • Hiroshi Takamori
    • 1
  • Tomohiro Namimoto
    • 2
  • Ken-Ichi Iyama
    • 3
  • Hideo Baba
    • 1
  1. 1.Department of Gastroenterological Surgery, Graduate School of Medical SciencesKumamoto UniversityKumamotoJapan
  2. 2.Department of Diagnostic Radiology, Graduate School of Medical SciencesKumamoto UniversityKumamotoJapan
  3. 3.Department of Surgical PathologyKumamoto University HospitalKumamotoJapan