Pigmented hepatocellular adenoma: Report of a case
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- Masuda, T., Beppu, T., Ikeda, K. et al. Surg Today (2011) 41: 881. doi:10.1007/s00595-010-4344-7
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Hepatocellular adenoma is a rare, benign neoplasm that is related to the use of contraceptives or androgenicanabolic steroids. A 51-year-old man with no history of steroid use was found to have a liver tumor. Plain computed tomography showed a high-density tumor that was enhanced in the arterial phase, and the enhancement was prolonged in the delayed phase. Magnetic resonance imaging showed that the tumor was hyperintense on in- and opposed-phase T1-weighted gradient recalled echo images and hyperintense on T1-weighted spin echo images. A partial hepatic resection was performed. A histological examination revealed normal hepatocyte-like tumor cells, composed of abundant dark brown granules of Dubin-Johnson-like pigment, which stained positively for Masson-Fontana stain. The tumor was diagnosed to be a very rare hepatocellular adenoma with the deposition of Dubin-Johnson-like pigment.