Surgery Today

, Volume 40, Issue 9, pp 883–889

Solitary hepatic lymphangioma: Report of a case

Authors

  • Takuya Matsumoto
    • Pathology DivisionNational Cancer Center Hospital
    • Hepatobiliary and Pancreatic Surgery DivisionNational Cancer Center Hospital
  • Hidenori Ojima
    • Pathology DivisionNational Cancer Center Research Institute
  • Yuri Akishima-Fukasawa
    • Pathology DivisionNational Cancer Center Research Institute
  • Nobuyoshi Hiraoka
    • Pathology DivisionNational Cancer Center Research Institute
  • Hiroaki Onaya
    • Diagnostic Radiology DivisionNational Cancer Center Hospital
  • Kazuaki Shimada
    • Hepatobiliary and Pancreatic Surgery DivisionNational Cancer Center Hospital
  • Yasunori Mizuguchi
    • Diagnostic Radiology DivisionNational Cancer Center Hospital
  • Shintaro Sakurai
    • Department of SurgerySt. Luke’s International Hospital
  • Toshiharu Ishii
    • Department of PathologyToho University School of Medicine
  • Tomoo Kosuge
    • Hepatobiliary and Pancreatic Surgery DivisionNational Cancer Center Hospital
  • Yae Kanai
    • Pathology DivisionNational Cancer Center Research Institute
Case Report

DOI: 10.1007/s00595-010-4255-7

Cite this article as:
Matsumoto, T., Ojima, H., Akishima-Fukasawa, Y. et al. Surg Today (2010) 40: 883. doi:10.1007/s00595-010-4255-7

Abstract

A 52-year-old woman presented with upper abdominal pain. Abdominal ultrasonography showed a 4-cm well-defined mass containing solid and cystic components in segment IV of the liver, and contrast-enhanced T1-weighted magnetic resonance imaging revealed heterogeneous enhancement within the tumor, indicating a solid or fibrous component. There were no cystic lesions in any other organs. A partial hepatectomy was performed, based on a preoperative diagnosis of sclerosing hemangioma and biliary cystadenoma or cystadenocarcinoma. Pathologically, the tumor appeared to be a multilocular and cystic lesion lined by attenuated endothelial- like cells with no atypia. Immunohistochemistry demonstrated the endothelial-like cells to be positive for the lymphatic-specific markers D2-40, LYVE-1, and Prox-1, which proved helpful for confirming the diagnosis as solitary hepatic lymphangioma. This case is presented with details of the pathologic and radiologic findings, because solitary hepatic lymphangioma is an extremely rare tumor and no previous reports have provided details of the immunohistochemical characteristics.

Key words

Solitary hepatic lymphangiomaD2-40LYVE-1Prox-1Hemangioma

Copyright information

© Springer 2010