Surgery Today

, Volume 39, Issue 7, pp 587–591

Aloe versus silver sulfadiazine creams for second-degree burns: A randomized controlled study

Authors

  • Ghasemali Khorasani
    • Department of Surgery, Faculty of MedicineMazandaran University of Medical Sciences
    • Faculty of MedicineTehran University of Medical Sciences
    • Department of Medicinal Chemistry, Faculty of PharmacyMazandaran University of Medical Sciences
    • Pharmaceutical Research CenterMazandaran University of Medical Sciences
  • Mohammad Azadbakht
    • Department of Pharmacognosy, Faculty of PharmacyMazandaran University of Medical Sciences
  • Arman Zamani
    • Department of Surgery, Faculty of MedicineMazandaran University of Medical Sciences
  • Mohammad Reza Mahdavi
    • Department of Clinical Laboratory, Faculty of Paramedical SciencesMazandaran University of Medical Sciences
Original Article

DOI: 10.1007/s00595-008-3944-y

Cite this article as:
Khorasani, G., Hosseinimehr, S.J., Azadbakht, M. et al. Surg Today (2009) 39: 587. doi:10.1007/s00595-008-3944-y

Abstract

Purpose

Burn injury is associated with a high incidence of death and disability; yet its management remains problematic and costly. We conducted this clinical study to evaluate the efficacy of aloe vera cream for partial thickness burn wounds and compare its results with those of silver sulfadiazine (SSD).

Methods

Thirty patients with similar types of second-degree burns at two sites on different parts of the body were included in this study. Each patient had one burn treated with topical SSD and one treated with aloe cream, randomly.

Results

The rate of re-epithelialization and healing of the partial thickness burns was significantly faster in the site treated with aloe than in the site treated with SSD (15.9 ± 2 vs 18.73 ± 2.65 days, respectively; P < 0.0001). The sites treated with aloe were completely healed in less than 16 days vs 19 days for the sites treated with SSD.

Conclusion

These results clearly demonstrated the greater efficacy of aloe cream over SSD cream for treating second-degree burns.

Key words

BurnAloe veraWoundSilver sulfadiazine

Copyright information

© Springer 2009