Surgery Today

, Volume 37, Issue 1, pp 38–42

Primary Rhabdomyosarcoma of the Breast in a 13-Year-Old Girl: Report of a Case

  • Hiroko Nogi
  • Tadashi Kobayashi
  • Kazumi Kawase
  • Isao Tabei
  • Yasuo Toriumi
  • Masafumi Suzuki
  • Makio Kawakami
  • Toshiaki Morikawa
  • Ken Uchida
Article

DOI: 10.1007/s00595-006-3326-2

Cite this article as:
Nogi, H., Kobayashi, T., Kawase, K. et al. Surg Today (2007) 37: 38. doi:10.1007/s00595-006-3326-2

Abstract

We report a case of primary alveolar rhabdomyosarcoma of the breast in a 13-year-old Japanese girl. The patient initially presented with a 13 × 8-cm mass in her left breast, which was diagnosed as alveolar rhabdomyosarcoma after an excisional biopsy. Genetic expression of the tumor revealed t(2;13)(q35–37;q14). She underwent modified radical mastectomy (Bt + Ax) and nine lymph nodes were found to be involved. Systemic examinations showed multiple bone and lung metastases 2 weeks after her operation. Despite chemotherapy with doxorubicin, ifosfamide, and actinomycin D, which resulted in remission for 6 months, she died of the disease 8 months after surgery.

Key words

RhabdomyosarcomaBreastGirl

Copyright information

© Springer-Verlag Tokyo 2007

Authors and Affiliations

  • Hiroko Nogi
    • 1
  • Tadashi Kobayashi
    • 2
  • Kazumi Kawase
    • 1
  • Isao Tabei
    • 1
  • Yasuo Toriumi
    • 1
  • Masafumi Suzuki
    • 3
  • Makio Kawakami
    • 3
  • Toshiaki Morikawa
    • 4
  • Ken Uchida
    • 1
  1. 1.Department of Breast and Endocrine SurgeryJikei University School of MedicineTokyoJapan
  2. 2.Department of Clinical OncologyJikei University School of MedicineTokyoJapan
  3. 3.Department of PathologyJikei University School of MedicineTokyoJapan
  4. 4.Department of Respiratory SurgeryJikei University School of MedicineTokyoJapan