Acta Diabetologica

, Volume 51, Issue 3, pp 395–402

Changes in weight and BMI following the diagnosis of type 1 diabetes in children and adolescents

  • L. de Vries
  • M. Bar-Niv
  • Y. Lebenthal
  • A. Tenenbaum
  • S. Shalitin
  • L. Lazar
  • A. Cohen
  • M. Phillip
Original Article

DOI: 10.1007/s00592-013-0524-4

Cite this article as:
de Vries, L., Bar-Niv, M., Lebenthal, Y. et al. Acta Diabetol (2014) 51: 395. doi:10.1007/s00592-013-0524-4

Abstract

The aim of this study was to study weight and body mass index (BMI) before, at, and after diagnosis of type 1 diabetes (T1D) and to identify factors associated with weight gain. Studied retrospectively were 209 children <18 years with T1D followed for 6 years. Data collected included clinical and laboratory data before diagnosis, at diagnosis, and during 6 years of follow-up. Anthropometric parameters of patients were compared along follow-up and with those of their parents and siblings. Mean BMI–standard deviation score (SDS) was below average at diagnosis (−0.66 ± 1.27), had increased to 0.37 ± 0.93 at 3 months, and decreased to a nadir at 6 months in females and 12 months in males; between 1 and 3 years, there was a slight increase and between 3 and 6 years a further increase only in the females. BMI–SDS at 6 years was significantly higher than pre-diabetes BMI–SDS (0.35 ± 0.83 vs. −0.04 ± 1.23, p < 0.001). Patients’ BMI–SDS at 6 years was similar to that of their parents and siblings, was higher in the females (0.53 ± 0.74 vs. 0.27 ± 0.82, p = 0.02) and in those keeping diabetes a secret (0.66 ± 0.82 vs. 0.33 ± 0.78, p = 0.027), and was not associated with age or pubertal stage at diagnosis, ethnicity, or metabolic control. A longer duration of insulin pump therapy was associated with a lower BMI–SDS (r = −0.2375, p < 0.025). BMI–SDS increased during the 6 years following diagnosis of T1D in pediatric patients, especially in the females, but remained in the normal range and was similar to that of other family members.

Keywords

Type 1 diabetes mellitus Body mass index Weight standard deviation score Insulin pump therapy Obesity Overweight 

Copyright information

© Springer-Verlag Italia 2013

Authors and Affiliations

  • L. de Vries
    • 1
    • 2
  • M. Bar-Niv
    • 2
  • Y. Lebenthal
    • 1
    • 2
  • A. Tenenbaum
    • 1
  • S. Shalitin
    • 1
    • 2
  • L. Lazar
    • 1
    • 2
  • A. Cohen
    • 3
    • 4
  • M. Phillip
    • 1
    • 2
  1. 1.The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood DiabetesSchneider Children’s Medical Center of IsraelPetah TikvaIsrael
  2. 2.Sackler Faculty of MedicineTel Aviv UniversityTel AvivIsrael
  3. 3.Siaal Research Center for Family Medicine and Primary Care, Faculty of Health SciencesBen-Gurion University of the NegevBeer-ShevaIsrael
  4. 4.Israel Chief Physician OfficeClalit Health ServicesTel AvivIsrael

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