Acta Diabetologica

, Volume 51, Issue 1, pp 43–51

Health-related quality of life and treatment preferences in adolescents with type 1 diabetes. The VIPKIDS study

  • V. Cherubini
  • R. Gesuita
  • R. Bonfanti
  • A. Franzese
  • A. P. Frongia
  • D. Iafusco
  • A. Iannilli
  • F. Lombardo
  • I. Rabbone
  • A. Sabbion
  • A. Salvatoni
  • A. Scaramuzza
  • R. Schiaffini
  • N. Sulli
  • S. Toni
  • S. Tumini
  • A. Mosca
  • F. Carle
  • VIPKIDS Study Group
Original Article

DOI: 10.1007/s00592-013-0466-x

Cite this article as:
Cherubini, V., Gesuita, R., Bonfanti, R. et al. Acta Diabetol (2014) 51: 43. doi:10.1007/s00592-013-0466-x

Abstract

A multi-centre, observational, cross-sectional study was carried out to determine whether the health-related quality of life (HRQOL) of adolescents with type 1 diabetes is affected by different insulin treatment systems, and which features of HRQOL are impacted by the respective insulin treatment. The study regarded 577 adolescents, aged 10–17 years, with type 1 diabetes treated with continuous subcutaneous insulin infusion (CSII) (n = 306) or multiple daily injections (MDI) (n = 271). The Insulin Delivery System Rating Questionnaire was validated in Italian and was self-completed by the subjects during a routine visit to the centres. Subjects were compared following the domains of the questionnaire. Good HRQOL was seen in subjects treated with either MDI or CSII. Significant differences were not found in the domains for general diabetes, including diabetes worries, social burden and psychological well-being. Multiple quantile regression analysis showed that CSII confers significant advantages in terms of HRQOL with improvements in treatment satisfaction, perceived clinical efficacy and reduction in treatment interference with daily activities. This favourable impact was more evident in subjects reporting lower HRQOL scores, suggesting that CSII may be especially useful for individuals perceiving a poor HRQOL. Analysis of the domains indicated that CSII was associated with a higher HRQOL than MDI. Life-course HRQOL evaluation using a standardised questionnaire can ensure better chronic disease management. This is particularly important when providing individualised care for adolescents, as they become increasingly responsible for managing their diabetes.

Keywords

CSII Quality of life Diabetes in childhood Devices Psychological aspects 

Copyright information

© Springer-Verlag Italia 2013

Authors and Affiliations

  • V. Cherubini
    • 1
  • R. Gesuita
    • 2
  • R. Bonfanti
    • 3
  • A. Franzese
    • 4
  • A. P. Frongia
    • 5
  • D. Iafusco
    • 6
  • A. Iannilli
    • 7
  • F. Lombardo
    • 8
  • I. Rabbone
    • 10
  • A. Sabbion
    • 9
  • A. Salvatoni
    • 11
  • A. Scaramuzza
    • 12
  • R. Schiaffini
    • 13
  • N. Sulli
    • 14
  • S. Toni
    • 15
  • S. Tumini
    • 16
  • A. Mosca
    • 17
  • F. Carle
    • 2
  • VIPKIDS Study Group
  1. 1.Division of Pediatric Diabetes, Maternal-Infant DepartmentAOU OO RR Ancona, “G. Salesi” HospitalAnconaItaly
  2. 2.Centre of Epidemiology and BiostatisticsPolytechnic University of MarcheAnconaItaly
  3. 3.Centre of Paediatric DiabetologySan Raffaele HospitalMilanItaly
  4. 4.Centre of Paediatric DiabetologyUniversity Federico IINaplesItaly
  5. 5.Unit of Paediatric DiabetesBrotzu HospitalCagliariItaly
  6. 6.Centre of Paediatric DiabetologySecond University of NaplesNaplesItaly
  7. 7.Maternal-Infant DepartmentAOU OO RR AnconaAnconaItaly
  8. 8.Department of PaediatricsUniversity of MessinaMessinaItaly
  9. 9.Centre of Paediatric DiabetologyUniversity of VeronaVeronaItaly
  10. 10.SCDU Paediatric DiabetesUniversity of TurinTurinItaly
  11. 11.Department of PaediatricsInsubria UniversityVareseItaly
  12. 12.Centre of Paediatric DiabetologySacco HospitalMilanItaly
  13. 13.Centre of Paediatric DiabetologyBambino Gesù HospitalRomeItaly
  14. 14.Centre of Paediatric DiabetologyUniversity La SapienzaRomeItaly
  15. 15.Centre of Paediatric DiabetologyAOU MeyerFlorenceItaly
  16. 16.Centre of Paediatric DiabetologyUniversity of ChietiChietiItaly
  17. 17.Department of Sciences and Biomedical TechnologiesUniversity of MilanMilanItaly

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