Acta Diabetologica

, Volume 50, Issue 5, pp 713–719

High meat consumption is associated with type 1 diabetes mellitus in a Sardinian case–control study

  • Sandro Muntoni
  • Roberto Mereu
  • Luigi Atzori
  • Alessandra Mereu
  • Sabrina Galassi
  • Stefania Corda
  • Paola Frongia
  • Efisio Angius
  • Paolo Pusceddu
  • Paolo Contu
  • Francesco Cucca
  • Mauro Congia
  • Sergio Muntoni
Original Article

DOI: 10.1007/s00592-012-0385-2

Cite this article as:
Muntoni, S., Mereu, R., Atzori, L. et al. Acta Diabetol (2013) 50: 713. doi:10.1007/s00592-012-0385-2

Abstract

The large worldwide variation in type 1 diabetes incidence and increasing incidence over time points toward important environmental risk factors. Among them, nutrition plays an important role. The objective was to investigate the relationship between type 1 diabetes and nutritional factors in pregnancy and early in life. We carried out, using semi-quantitative food frequency questionnaires, a retrospective case–control study in 298 children of 0–15 years old, 145 of which were affected by type 1 diabetes. The diet of all children and of their mothers during pregnancy and lactation was assessed. In children, a statistically significant dose–response association between type 1 diabetes and the amount of meat consumption was found while no other nutritional factors were associated with the disease. High meat consumption seems to be an important early in life cofactor for type 1 diabetes development, although these findings need to be confirmed in wider prospective follow-up studies.

Keywords

Meat Insulin-dependent diabetes mellitus Sardinia Increasing incidence 

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Sandro Muntoni
    • 1
    • 2
  • Roberto Mereu
    • 1
  • Luigi Atzori
    • 1
  • Alessandra Mereu
    • 3
  • Sabrina Galassi
    • 2
  • Stefania Corda
    • 2
  • Paola Frongia
    • 4
  • Efisio Angius
    • 4
  • Paolo Pusceddu
    • 4
  • Paolo Contu
    • 3
  • Francesco Cucca
    • 5
  • Mauro Congia
    • 6
  • Sergio Muntoni
    • 2
  1. 1.Unit of Oncology and Molecular Pathology, Department of ToxicologyUniversity of CagliariCagliariItaly
  2. 2.Centre for Metabolic Diseases and Atherosclerosis, The ME.DI.CO. AssociationCagliariItaly
  3. 3.Department of Public HealthUniversity of CagliariCagliariItaly
  4. 4.Division of PaediatricsS. Michele HospitalCagliariItaly
  5. 5.Department of Biomedical SciencesUniversity of SassariSassariItaly
  6. 6.Department of Biomedical Science and BiotechnologiesUniversity of CagliariCagliariItaly

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