Acta Diabetologica

, Volume 44, Issue 1, pp 20–22

Measurement of salivary adiponectin levels


DOI: 10.1007/s00592-007-0236-8

Cite this article as:
Toda, M., Tsukinoki, R. & Morimoto, K. Acta Diabetol (2007) 44: 20. doi:10.1007/s00592-007-0236-8


We designed a method for measuring salivary adiponectin. In 188 healthy males, salivary adiponectin levels were measured using a commercial enzyme immunoassay kit for plasma with minor modifications. Intra- and inter-assay coefficients of variation for salivary adiponectin ranged from 0.6 to 4.9 and 1.1 to 9.8%, respectively. Salivary adiponectin levels ranged from 0.37 to 6.42 ng/ml, exceeding the kit's detection limit. For the over-43 age group, there was a significant correlation between plasma and salivary adiponectin levels (p<0.000001). These findings suggest the possibilities of salivary adiponectin as a marker of increased risk of non-insulindependent diabetes mellitus or cardiovascular disease.

Key words

Adiponectin Measurement Saliva Plasma 

Copyright information

© Springer-Verlag Italia 2007

Authors and Affiliations

  1. 1.Department of Social and Environmental MedicineOsaka University Graduate School of MedicineOsakaJapan

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