Measurement of salivary adiponectin levels
- Cite this article as:
- Toda, M., Tsukinoki, R. & Morimoto, K. Acta Diabetol (2007) 44: 20. doi:10.1007/s00592-007-0236-8
We designed a method for measuring salivary adiponectin. In 188 healthy males, salivary adiponectin levels were measured using a commercial enzyme immunoassay kit for plasma with minor modifications. Intra- and inter-assay coefficients of variation for salivary adiponectin ranged from 0.6 to 4.9 and 1.1 to 9.8%, respectively. Salivary adiponectin levels ranged from 0.37 to 6.42 ng/ml, exceeding the kit's detection limit. For the over-43 age group, there was a significant correlation between plasma and salivary adiponectin levels (p<0.000001). These findings suggest the possibilities of salivary adiponectin as a marker of increased risk of non-insulindependent diabetes mellitus or cardiovascular disease.