Abstract
This paper presents a novel design of a differential C4D (DC4D) sensor based on three electrodes for both conductive and non-conductive fluidic channel. This structure consists of two single C4D with an applied carrier sinusoidal signal to the center electrode as the excitation electrode. The electrodes are directly bonded on the PCB with built-in differential amplifier and signal processing circuit in order to reduce the parasitic component and common noise. In the non-conductive fluidic channel, the output voltage and capacitance changes 214.39 mV and 14 fF, respectively when a 3.83 μl tin particle crosses an oil channel. In conductive fluidic channel, the output voltage and admittance change up to 300 mV and 0.07 μS for the movement of a 4.88 μl plastic particle through channel. Moreover, the voltage change of this sensor is linear relation with the volume of investigated particle. This sensor also allows measuring velocity of particle inside fluidic channel and resistivity of the conductive fluidic.
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References
Brito-Neto JGA, da Silva JAF, Blanes L, do Lago CL (2005) Understanding capacitively coupled contactless conductivity detection in capillary and microchip electrophotrsis. Part 2. Peak shape, stray capacitance, noise, and actual electronics. Electroanalysis 17:1207–1214
da Silva JAF, do Lago CL (1998) An oscillometric detector for capillary electrophoresis. Anal Chem 70(20):4339–4343
Demori M, Ferrari V, Strazza D, Poesio P (2010) A capacitive sensor system for the analysis of two-phase flows of oil and conductive water. Sens Actuators A 163(1):172–179
Gas B, Zuska J, Coufal P, van de Goor T (2002) Optimization of the high-frequency contactless conductivity detector for capillary electrophoresis. Electrophoresis 23:3520–3527
Gong X-Y (2008) Applications of capillary electrophoresis with contactless conductivity detection. PhD thesis, Basel University
Huang Z, Long J, Xu W, Ji H, Wang B, Li H (2012) Design of capacitively coupled contactless conductivity detection sensor. Flow Meas Instrum 27:67–70
Jaworek A, Krupa A, Trela M (2004) Capacitance sensor for void fraction measurement in water/steam flows. Flow Meas Instrum 15(5–6):317–324
Kuban P, Hauser PC (2004a) Fundamental aspects of contactless conductivity detection for capillary electrophoresis, part I: frequency behavior and cell geometry. Electrophoresis 25:3387–3397
Kuban P, Hauser PC (2004b) Fundamental aspects of contactless conductivity detection for capillary electrophoresis, part II: signal-to-noise ratio and stray capacitance. Electrophoresis 25:3398–3405
Kuban P, Hauser PC (2008) A review of the recent achievements in capacitively coupled contactless conductivity detection. Anal Chim Acta 607(1):15–29
Kuban P, Hauser PC (2011) Capacitively coupled contactless conductivity detection for micro separation techniques—recent development. Electrophoresis 32:30–42
Kuban P, Karlberga B, Kuban P, Kuban V (2002) Application of a contactless conductometric detector for the simultaneous determination of small anions and cations by capillary electrophoresis with dual-opposite end injection. J Chromatogr A 964:227–241
Liu J, An L, Xu Z, Wang N, Yan X, Du L, Liu C, Wang L (2013) Modeling of capacitively coupled contactless conductivity detection on microfluidic chips. Microsyst Technol 19(12):1991–1996
Opekar F, Tuma P, Stulik K (2013) Contactless impedance sensors and their application to flow measurements. Sensors (Basel) 13(3):2786–2801
Quoc TV, Dac HN, Quoc TP, Dinh DN, Duc TC (2015) A printed circuit board capacitive sensor for air bubble inside fluidic flow detection. Microsyst Technol 21:911–918
Shih C-Y, Li W, Zheng SY, Tai YC (2006) A resonance-induced resolution enhancement method for conductivity sensor. In: Proceeding of 5th IEEE conference on sensors, EXCO, pp 271–274
Solinova V, Kasicka V (2006) Recent applications of conductivity detection in capillary and chip electrophoresis. J Sep Sci 29:1743–1762
Strazza D, Demori M, Ferrari V, Poesio P (2011) Capacitance sensor for hold-up measurement in high-viscous-oil/conductive-water core-annular flows. Flow Meas Instrum 22(5):360–369
Wang L, Huang Z, Wang B, Ji H, Li H (2012) Flow pattern identification of gas-liquid two-phase flow based on capacitively coupled contactless conductivity detection. IEEE Trans Instrum Measure 61(5):1466–1474
Wang B, Zhou Y, Ji H, Huang Z, Li H (2013) Measurement of bubble velocity using Capacitively Coupled Contactless Conductivity Detection (C4D) technique. Particuology 11(2):198–203
Zemann AJ, Schnell E, Volgger D, Bonn GK (1998) Contactless conductivity detection for capillary electrophoresis. Anal Chem 70:563–567
Zhang Z, Li D, Liu X, Subhani Q, Zhu Y, Kang Q, Shen D (2012) Determination of anions using monolithic capillary column ion chromatography with end-to-end differential contactless conductometric detectors under resonance approach. Analyst 137(12):2876–2883
Zhang Z, Li Y, Xu Z, Zhu X, Kang Q, Shen D (2013) Determination of equivalent circuit paramerters of a contactless conductive detector in capillary electrophoresis by an imperdance analysis method. Electrochem Sci 8:3357–3370
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This research is funded by Vietnam National Foundation for Science and Technology Development (NAFOSTED) under grant number 103.01-2011.59.
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Hai, N.D., Tuan, V.Q., Loc, D.Q. et al. Differential C4D sensor for conductive and non-conductive fluidic channel. Microsyst Technol 22, 2511–2520 (2016). https://doi.org/10.1007/s00542-015-2586-4
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DOI: https://doi.org/10.1007/s00542-015-2586-4