Journal of Gastroenterology

, Volume 36, Issue 2, pp 129–132

Primary intestinal lymphangiectasia successfully treated with octreotide

Authors

  • Ganji Kuroiwa
    • Fourth Department of Internal Medicine, Sapporo Medical University, South-1, West-16, Chuo-ku, Sapporo 060-8543, Japan
  • Tetsuji Takayama
    • Fourth Department of Internal Medicine, Sapporo Medical University, South-1, West-16, Chuo-ku, Sapporo 060-8543, Japan
  • Yasushi Sato
    • Fourth Department of Internal Medicine, Sapporo Medical University, South-1, West-16, Chuo-ku, Sapporo 060-8543, Japan
  • Yasuo Takahashi
    • Fourth Department of Internal Medicine, Sapporo Medical University, South-1, West-16, Chuo-ku, Sapporo 060-8543, Japan
  • Tomoki Fujita
    • Fourth Department of Internal Medicine, Sapporo Medical University, South-1, West-16, Chuo-ku, Sapporo 060-8543, Japan
  • Atsushi Nobuoka
    • Fourth Department of Internal Medicine, Sapporo Medical University, South-1, West-16, Chuo-ku, Sapporo 060-8543, Japan
  • Takehiro Kukitsu
    • Fourth Department of Internal Medicine, Sapporo Medical University, South-1, West-16, Chuo-ku, Sapporo 060-8543, Japan
  • Junji Kato
    • Fourth Department of Internal Medicine, Sapporo Medical University, South-1, West-16, Chuo-ku, Sapporo 060-8543, Japan
  • Sumio Sakamaki
    • Fourth Department of Internal Medicine, Sapporo Medical University, South-1, West-16, Chuo-ku, Sapporo 060-8543, Japan
  • Yoshiro Niitsu
    • Fourth Department of Internal Medicine, Sapporo Medical University, South-1, West-16, Chuo-ku, Sapporo 060-8543, Japan
Case report

DOI: 10.1007/s005350170142

Cite this article as:
Kuroiwa, G., Takayama, T., Sato, Y. et al. J Gastroenterol (2001) 36: 129. doi:10.1007/s005350170142

Abstract:

A 21-year-old man with diarrhea and edema was admitted to our hospital and diagnosed with protein-losing enteropathy caused by primary intestinal lymphangiectasia. He was placed, in turn, on a low-fat diet, an elemental diet, and, subsequently, fasting therapy with total parenteral nutrition (TPN) support. However, his symptoms were not relieved, but, rather were exacerbated. On the 45th day of hospitalization, octreotide therapy was initiated. After 2 weeks of treatment, his clinical symptoms, as well as hypoproteinemia and hypoalbuminemia, gradually became alleviated. The improvement was confirmed in terms of scintigraphy, endoscopy, and histology of the duodenum. The patient remained healthy until 6 months after the commencement of octreotide treatment, when he discontinued octreotide at his own discretion, at which point the symptoms recurred. Resumption of the drug; however, again brought about remission, which has continued until the present, March 2000. Thus, octreotide therapy is one modality which may be useful for refractory primary intestinal lymphangiectasia.

Key words: octreotide lymphangiectasia protein-losing enteropathy

Copyright information

© Springer-Verlag Tokyo 2001