Journal of Gastroenterology

, Volume 35, Issue 11, pp 849–855

Tumor-detecting capacity and clinical usefulness of SPIO-MRI in patients with hepatocellular carcinoma

  • Hiroshi Nakamura
  • Naoki Ito
  • Fumio Kotake
  • Yuji Mizokami
  • Takeshi Matsuoka

DOI: 10.1007/s005350070022

Cite this article as:
Nakamura, H., Ito, N., Kotake, F. et al. J Gastroenterol (2000) 35: 849. doi:10.1007/s005350070022

Abstract:

The tumor-detecting capacity and clinical usefulness of superparamagnetic iron oxide (SPIO) magnetic resonance imaging (MRI) were examined in patients with hepatocellular carcinoma. The tumor detection rate of SPIO-MRI (64.5%) was comparable to those of dynamic computed tomography (CT) and plain MRI, but lower than that for Gd dynamic MRI (93.5%; P < 0.01%). A combination of Gd dynamic MRI and SPIO-MRI improved the detection rate; further, the tumor stage with respect to tumor blood-flow pattern was predicted by combining plain MRI with SPIO-MRI. This combination procedure may also be useful for selecting therapeutic strategies.

Key words: superparamagnetic iron oxide (SPIO) hepatocellular carcinoma (HCC) magnetic resonance imaging (MRI) 

Copyright information

© Springer-Verlag Tokyo 2000

Authors and Affiliations

  • Hiroshi Nakamura
    • 1
  • Naoki Ito
    • 2
  • Fumio Kotake
    • 2
  • Yuji Mizokami
    • 1
  • Takeshi Matsuoka
    • 1
  1. 1.Fifth Department of Internal Medicine, Tokyo Medical University Kasumigaura Hospital, 3-20-1 Ami-cho chuo, Ibaraki 300-0395, JapanJP
  2. 2.Department of Radiology, Tokyo Medical University, Tokyo, JapanJP

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