Journal of Gastroenterology

, Volume 34, Issue 3, pp 383–386

Gastric enterochromaffin-like-cell tumor with liver and splenic metastases

  • Naofumi Eriguchi
  • Shigeaki Aoyagi
  • Masao Hara
  • Takenori Sakai
  • Hiroyasu Imayama
  • Eiji Tanaka
  • Mitsuo Hashimoto
  • Ichiro Imamura
  • Masayoshi Kage

DOI: 10.1007/s005350050279

Cite this article as:
Eriguchi, N., Aoyagi, S., Hara, M. et al. J Gastroenterol (1999) 34: 383. doi:10.1007/s005350050279

Abstract:

We report a patient with gastric enterochromaffin-like-cell tumor with liver and splenic metastases. He was 68 years old and presented with major complaints of epigastric pain and weight loss. Under the diagnosis of gastric carcinoma with liver metastasis, total gastrectomy with splenectomy and lateral seg-mentectomy of the liver was performed. Intraoperative findings resulted in a diagnosis of adenocarcinoma T3N2P0H1, in stage IVa. Histological examination of the resected specimens showed a well differentiated neuroendocrine carcinoma (enterochromaffin-like-cell tumor) with liver and splenic metastasis which demonstrated high-grade lymphatic and vascular invasion. There was no lymph node metastasis. The tumor cells in the stomach, liver and spleen were immunoreactive for chromogranin A and Grimelius—positive. We review the literature, as well as presenting this case report.

Key words: enterochromaffin-like-cell tumorliver and splenic metastases

Copyright information

© Springer-Verlag Tokyo 1999

Authors and Affiliations

  • Naofumi Eriguchi
    • 1
  • Shigeaki Aoyagi
    • 1
  • Masao Hara
    • 1
  • Takenori Sakai
    • 1
  • Hiroyasu Imayama
    • 1
  • Eiji Tanaka
    • 1
  • Mitsuo Hashimoto
    • 1
  • Ichiro Imamura
    • 1
  • Masayoshi Kage
    • 2
  1. 1.Department of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, JapanJP
  2. 2.Department of Pathology, Kurume University School of Medicine, Kurume, JapanJP