Journal of Gastroenterology

, Volume 41, Issue 5, pp 418–424

Dietary habits and stomach cancer in Mizoram, India

Authors

  • Rup Kumar Phukan
    • Regional Medical Research CentreN.E. Region (ICMR)
  • Konwar Narain
    • Regional Medical Research CentreN.E. Region (ICMR)
  • Eric Zomawia
    • Aizawl Civil Hospital
  • Nakul Chandra Hazarika
    • Regional Medical Research CentreN.E. Region (ICMR)
  • Jagadish Mahanta
    • Regional Medical Research CentreN.E. Region (ICMR)
Article

DOI: 10.1007/s00535-006-1761-x

Cite this article as:
Phukan, R., Narain, K., Zomawia, E. et al. J Gastroenterol (2006) 41: 418. doi:10.1007/s00535-006-1761-x

Abstract

Background

An extremely high prevalence of stomach cancer was observed in Mizoram (India), where the population consumes uncommon food. The relation of food habits and stomach cancer was examined in this study.

Methods

A hospital-based case-control study was conducted during 2001–2004 to determine the risk factors among 329 patients with histologically confirmed stomach cancer and 658 matched controls. Food habits were determined by personal interview.

Results

An elevated risk of stomach cancer was observed with frequent consumption of sa-um [odds ratio (OR) 3.4] (sa-um is fermented pork fat, a traditional food) and with frequent consumption of smoked dried salted meat (OR 2.8) and fish (OR 2.5). Soda (alkali), used as a food additive, increased the risk of stomach cancer (OR 2.9). Helicobacter pylori infection was not found to be an independent risk factor for carcinogenesis of stomach cancer in this study. However, when H. pylori infection interacted with consumption of sa-um or smoked dried meat, it showed a significant association.

Conclusion

Peculiar food habits in Mizoram might be associated with the high prevalence of stomach cancer in Mizoram along with other factors. H. pylori infection might increase the risk of stomach cancer, or it may play a role as a promoter of stomach cancer in Mizoram.

Key words

stomach cancer smoked dried fish and meat dietary habits sa-um Mizoram

Copyright information

© Springer-Verlag Tokyo 2006