Journal of Gastroenterology

, Volume 39, Issue 11, pp 1110–1113

Obstructive jaundice caused by enteropathy-associated T-cell lymphoma in a patient with celiac sprue


  • Martin Buess
    • Medizinische Universitätsklinik Kantonsspital Bruderholz
  • Michael Steuerwald
    • Medizinische Universitätsklinik Kantonsspital Bruderholz
  • Werner Wegmann
    • Kantonales Institut für Pathologie Liestal
  • Madeleine Rothen
    • Medizinische Universitätsklinik Kantonsspital Bruderholz
Case report

DOI: 10.1007/s00535-004-1453-3

Cite this article as:
Buess, M., Steuerwald, M., Wegmann, W. et al. J Gastroenterol (2004) 39: 1110. doi:10.1007/s00535-004-1453-3


Patients with celiac sprue carry a considerable risk of gastrointestinal malignancies; in particular, non-Hodgkin’s lymphoma. These malignancies represent the most serious complications of celiac disease. Commonly, patients present with deteriorating symptoms of the underlying disease, which makes an early diagnosis difficult. We report a patient with a 13-year history of celiac sprue presenting with painless jaundice and a Courvoisier gallbladder. Abdominal computed tomography (CT) scan showed thickening of the duodenal wall, suggesting a neoplastic infiltration of the papilla of Vater, causing biliary obstruction. Biopsies taken on endoscopy revealed enteropathy-associated T-cell lymphoma of the duodenum. Biliary obstruction is a rare clinical finding in enteropathy-associated T-cell lymphoma. To our knowledge, this is the first reported case of this unusual manifestation in celiac disease.

Key words

celiac diseaseT-cell non-Hodgkin’s lymphomaCourvoisier gallbladdercholestasis

Copyright information

© Springer-Verlag Tokyo 2004