Journal of Hepato-Biliary-Pancreatic Surgery

, Volume 14, Issue 6, pp 586–589

Cystic endocrine tumor of the pancreas with an atypical multilocular appearance

Authors

  • Masatoshi Kajiwara
    • Department of Hepatobiliary Pancreatic SurgeryNational Cancer Center Hospital East
  • Naoto Gotohda
    • Department of Hepatobiliary Pancreatic SurgeryNational Cancer Center Hospital East
  • Masaru Konishi
    • Department of Hepatobiliary Pancreatic SurgeryNational Cancer Center Hospital East
  • Toshio Nakagohri
    • Department of Hepatobiliary Pancreatic SurgeryNational Cancer Center Hospital East
  • Shinichiro Takahashi
    • Department of Hepatobiliary Pancreatic SurgeryNational Cancer Center Hospital East
  • Motohiro Kojima
    • Pathology Division, Research Center for Innovative OncologyNational Cancer Center Hospital East
  • Takahiro Hasebe
    • Surgical Pathology Section, Clinical Laboratory DivisionNational Cancer Center Hospital East
  • Taira Kinoshita
    • Department of Hepatobiliary Pancreatic SurgeryNational Cancer Center Hospital East
Case reports of interest

DOI: 10.1007/s00534-006-1218-x

Cite this article as:
Kajiwara, M., Gotohda, N., Konishi, M. et al. J Hepatobiliary Pancreat Surg (2007) 14: 586. doi:10.1007/s00534-006-1218-x

Abstract

A 46-year-old woman with epigastric pain was found to have a cystic tumor in the pancreas head on radiological examinations. The tumor was hypervascular, and its multilocular appearance resembled the “honeycomb” pattern of serous cystic tumor (SCT). The patient underwent surgery. The cut surface of the tumor showed a thick fibrous capsule with multiple cystic components, which contained necrotic tissue and brownish serous fluid, indicating an episode of hemorrhage. The cut surface of the tumor resembled solid-pseudopapillary tumor (SPT) on gross appearance. On immunohistochemical staining, the tumor cells showed diffuse and strong staining for synaptophysin (SYN), chromogranin A (CGA), and grimelius, and no staining for α 1-antitrypsin or CD10. We finally made a diagnosis of pancreatic endocrine tumor (PET). As PET sometimes shows an atypical multicystic appearance, immunohistochemical staining is mandatory for its correct diagnosis.

Key words

Cystic endocrine tumorPancreasMultilocularImmunohistochemical staining
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Copyright information

© Springer-Verlag Tokyo 2007