Journal of Hepato-Biliary-Pancreatic Surgery

, Volume 13, Issue 5, pp 370–377

Living-donor liver transplantation: an overview

Authors

  • Russell W. Strong
    • University of QueenslandPrincess Alexandra Hospital
Article

DOI: 10.1007/s00534-005-1076-y

Cite this article as:
Strong, R. J Hepatobiliary Pancreat Surg (2006) 13: 370. doi:10.1007/s00534-005-1076-y

Abstract

It has been 16 years since the first successful living-donor liver transplant was performed from a parent to a child. The overall recipient and graft survival, together with a low morbidity and mortality in donors, have resulted in the widespread acceptance of the procedure by both the transplant community and the public at large. Adult-to-adult living-donor liver transplantation has been evolving over the past decade. Despite living-donor transplant patients being better-risk candidates than those who receive a graft from a deceased donor, and well-established and experienced units achieving satisfactory results, overall recipient and graft survival recorder by registries can only be described as suboptimal. This, combined with the high morbidity and not-insignificant mortality amongst donors makes expansion of adult-to-adult liver transplantation hard to justify on a risk-benefit analysis.

Key words

Liver transplantationLiving donorRecipient outcomeDonor morbidityMortalityEthical issues

Copyright information

© Springer-Verlag Tokyo 2006