Supportive Care in Cancer

, Volume 21, Issue 7, pp 2067–2073

Acupuncture for cancer-related fatigue: a systematic review of randomized clinical trials

  • Paul Posadzki
  • Tae-Woong Moon
  • Tae-Young Choi
  • Tae-Yong Park
  • Myeong Soo Lee
  • Edzard Ernst
Review Article

DOI: 10.1007/s00520-013-1765-z

Cite this article as:
Posadzki, P., Moon, TW., Choi, TY. et al. Support Care Cancer (2013) 21: 2067. doi:10.1007/s00520-013-1765-z

Abstract

Purpose

Managing cancer-related fatigue (CRF) is an important element of the palliative care of cancer patients. The aim of this systematic review was to critically evaluate the effectiveness of acupuncture (AT) or electroacupuncture (EA) for CRF.

Methods

Fourteen databases were searched from their respective inception to November 2012. Randomized clinical trials (RCTs) of AT or EA for the treatment of CRF were considered for inclusion. The risk of bias/methodological quality was assessed using the method suggested by the Cochrane Collaboration.

Results

Seven RCTs met the eligibility criteria. Most were small pilot studies with serious methodological flaws. Four of the RCTs showed effectiveness of AT or AT in addition to usual care (UC) over sham AT, UC, enhanced UC, or no intervention for alleviating CRF. Three RCTs showed no effect of AT/EA over sham treatment.

Conclusion

Overall, the quantity and quality of RCTs included in the analysis were too low to draw meaningful conclusions. Even in the positive trials, it remained unclear whether the observed outcome was due to specific effects of AT/EA or nonspecific effects of care. Further research is required to investigate whether AT/EA demonstrates specific effects on CRF.

Keywords

AcupunctureCancerFatigueSystematic reviewEffectiveness

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Paul Posadzki
    • 1
    • 2
  • Tae-Woong Moon
    • 1
  • Tae-Young Choi
    • 1
  • Tae-Yong Park
    • 1
  • Myeong Soo Lee
    • 1
    • 2
  • Edzard Ernst
    • 2
  1. 1.Medical Research Division, KM Health Technology Research GroupKorea Institute of Oriental MedicineDaejeonSouth Korea
  2. 2.Complementary Medicine, Peninsula Medical SchoolUniversity of ExeterExeterUK