Supportive Care in Cancer

, Volume 14, Issue 10, pp 988–998

The clinical significance of quality of life assessments in oncology: a summary for clinicians

  • Jeff A. Sloan
  • Marlene H. Frost
  • Rick Berzon
  • Amylou Dueck
  • Gordon Guyatt
  • Carol Moinpour
  • Mirjam Sprangers
  • Carol Ferrans
  • David Cella
  • Clinical Significance Consensus Meeting Group
Special Article

DOI: 10.1007/s00520-006-0085-y

Cite this article as:
Sloan, J.A., Frost, M.H., Berzon, R. et al. Support Care Cancer (2006) 14: 988. doi:10.1007/s00520-006-0085-y
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Abstract

Background

A series of six manuscripts with an introduction appeared in the Mayo Clinic Proceedings, based upon the collective effort of 30 individuals with an interest and expertise in assessing the clinical significance of quality of life (QOL) assessments. The series of manuscripts described the state of the science of QOL assessments in oncology clinical research and practice and included extensive literature and theoretical justification for the continued inclusion of QOL in oncology clinical research and practice.

Objectives

The purpose of this paper is to produce a summary of these articles and to supplement these works with additional information that was gleaned from subsequent meetings and discussions of this material. The primary aim of this paper is to present a cogent and concise description for clinicians to facilitate the incorporation of QOL assessments into oncology clinical research and practice. The theoretical discussion is supplemented with an example of how the various ideas can be operationalized in an oncology clinical trial.

Keywords

QOLOncologyCancer

Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Jeff A. Sloan
    • 1
  • Marlene H. Frost
    • 2
  • Rick Berzon
    • 3
  • Amylou Dueck
    • 1
  • Gordon Guyatt
    • 5
  • Carol Moinpour
    • 6
  • Mirjam Sprangers
    • 7
  • Carol Ferrans
    • 8
  • David Cella
    • 9
  • Clinical Significance Consensus Meeting Group
  1. 1.Department of Health Sciences ResearchMayo Clinic and Mayo FoundationRochesterUSA
  2. 2.Women’s Cancer ProgramMayo Clinic and Mayo FoundationRochesterUSA
  3. 3.Corporate Health Economics and Market AccessBoehringer Ingelheim Pharmaceuticals, IncorporatedRidgefieldUSA
  4. 4.US Agency for International DevelopmentBureau for Global Health, Office of HIV/AIDSWashingtonUSA
  5. 5.Department of Clinical Epidemiology and BiostatisticsMcMaster University and Health Sciences CenterHamiltonCanada
  6. 6.Southwest Oncology Group Statistical CenterFred Hutchinson Cancer Research CenterSeattleUSA
  7. 7.Department of Medical Psychology, Academic Medical CenterUniversity of AmsterdamAmsterdamThe Netherlands
  8. 8.College of NursingUniversity of Illinois at ChicagoChicagoUSA
  9. 9.Center on Outcomes, Research and EducationEvanston Northwestern Healthcare and Northwestern UniversityChicagoUSA