Wiener klinische Wochenschrift

, Volume 126, Issue 5, pp 169–175

New AHA and ACC guidelines on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk

  • Gerald Klose
  • Frank Ulrich Beil
  • Hans Dieplinger
  • Arnold von Eckardstein
  • Bernhard Föger
  • Ioanna Gouni-Berthold
  • Franz Heigl
  • Wolfgang Koenig
  • Gert M. Kostner
  • Ulf Landmesser
  • Ulrich Laufs
  • Frank Leistikow
  • Winfried März
  • Georg Noll
  • Klaus G. Parhofer
  • Bernhard Paulweber
  • Walter F. Riesen
  • Jürgen R. Schaefer
  • Elisabeth Steinhagen-Thiessen
  • Armin Steinmetz
  • Hermann Toplak
  • Christoph Wanner
  • Eberhard Windler
perspective

DOI: 10.1007/s00508-014-0513-9

Cite this article as:
Klose, G., Beil, F., Dieplinger, H. et al. Wien Klin Wochenschr (2014) 126: 169. doi:10.1007/s00508-014-0513-9

Summary

After the publication of the new guidelines of the European Society of Cardiology and the European Atherosclerosis Society for the prevention and treatment of dyslipidemias (Eur Heart J 32:1769–1818, 2011; Eur Heart J 33:1635–1701, 2012), a group of authors has recently published on behalf of the American Heart Association and the American College of Cardiology guidelines on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk (Circulation 2013). These new guidelines are supposed to replace the until now widely accepted, at least in the USA, recommendations of the National Cholesterol Education Program Adult Treatment Panel III from the years 2002 (Circulation 106:3143–3421, 2002) and 2004 (Circulation 110:227–39, 2004). Furthermore, they claim to be based mainly on hard evidence derived from the interpretation of results of prospective randomized controlled trials. This Joint Position Statement of the Society for the Prevention of Cardiovascular Diseases e. V. (D.A.CH), the Austrian Atherosclerosis Society and the Working Group on Lipids and Atherosclerosis (AGLA) of the Swiss Society of Cardiology concludes that the use of individualized prevention strategies based on specific indications and LDL cholesterol target concentrations, a strategy whose worth has been widely proven and accepted for more than a decade in Europe, should not be given up.

Keywords

CholesterolLDL cholesterolCardiovascular diseaseAtherosclerosisGuidelinesStatins

Neue AHA und ACC-Leitlinie zur Risikoreduktion von Herz-Kreislauf-Erkrankungen durch Cholesterinsenkung (Gemeinsame Stellungnahme der D.A.CH-Gesellschaft Prävention von Herz-Kreislauf-Erkrankungen e.V., der Österreichischen Atherosklerose Gesellschaft und der Arbeitsgruppe Lipide und Atherosklerose (AGLA) der Schweizer Gesellschaft für Kardiologie)

Zusammenfassung

Nach der Publikation der Leitlinien der European Society of Cardiology (ESC) und der European Atherosclerosis Society (EAS) für die Prävention und Behandlung von Fettstoffwechselstörungen (Eur Heart J 32:1769-1818, 2011; Eur Heart J 33:1635-1701, 2012), hat kürzlich eine Autorengruppe im Namen der American Heart Association (AHA) und des American College of Cardiology (ACC) Leitlinien zur Absenkung des Risikos für Herz-Kreislauferkrankungen durch Cholesterinsenkung veröffentlicht (Circulation 2013). Diese neuen Leitlinien wollen, die bislang verbreitet, zumindest jedoch in den USA, akzeptierten Empfehlungen des NCEP/ATP (National Cholesterol Education Program Adult Treatment Panel) III aus den Jahren 2002 (Circulation 106:3121-3421, 2002) und 2004 (Circulation 110:227-39, 2004) abzulösen. Darüber hinaus beanspruchen sie, in erster Linie auf rigoroser Evidenz, hergeleitet aus der Interpretation von Ergebnissen prospektiver, randomisierter und kontrollierter Studien, zu beruhen.

Schlüsselwörter

CholesterinLDL-cholesterinKardiovaskuläre ErkrankungenAtheroskleroseStatine

Copyright information

© Springer-Verlag Wien 2014

Authors and Affiliations

  • Gerald Klose
    • 1
  • Frank Ulrich Beil
    • 2
  • Hans Dieplinger
    • 3
  • Arnold von Eckardstein
    • 4
  • Bernhard Föger
    • 5
  • Ioanna Gouni-Berthold
    • 6
  • Franz Heigl
    • 7
  • Wolfgang Koenig
    • 8
  • Gert M. Kostner
    • 9
  • Ulf Landmesser
    • 10
  • Ulrich Laufs
    • 11
  • Frank Leistikow
    • 12
  • Winfried März
    • 13
    • 14
    • 15
  • Georg Noll
    • 10
  • Klaus G. Parhofer
    • 16
  • Bernhard Paulweber
    • 17
  • Walter F. Riesen
    • 18
  • Jürgen R. Schaefer
    • 19
  • Elisabeth Steinhagen-Thiessen
    • 20
    • 21
  • Armin Steinmetz
    • 22
  • Hermann Toplak
    • 23
  • Christoph Wanner
    • 24
  • Eberhard Windler
    • 25
  1. 1.Practice for Internal Medicine, Gastroenterology, Cardiology and Preventive MedicineBremenGermany
  2. 2.Outpatient Clinic for Endocrinology and MetabolismUniversity Clinic Hamburg-EppendorfHamburgGermany
  3. 3.Section of Genetic Epidemiology, Department for Medical Genetics and Molecular and Clinical PharmacologyMedical UniversityInnsbruckAustria
  4. 4.Institute for Clinical ChemistryUniversity HospitalZurichSwitzerland
  5. 5.Department of Internal MedicineRegional Hospital BregenzBregenzAustria
  6. 6.Center for Endocrinology, Diabetes and Preventive MedicineUniversity of CologneCologneGermany
  7. 7.Medical Health Care Center Kempten-AllgäuKemptenGermany
  8. 8.Department of Internal Medicine II – CardiologyUniversity of Ulm Medical CenterUlmGermany
  9. 9.Institute for Molecular Biology und Biochemistry, Center for Molecular MedicineMedical UniversityGrazAustria
  10. 10.Cardiology ClinicUniversity HospitalZurichSwitzerland
  11. 11.Clinic for Internal Medicine III (Cardiology, Angiology and Medical Intensive Care)University Clinic of SaarlandHomburgGermany
  12. 12.Kidney Center MannheimMannheimGermany
  13. 13.Medical Clinic V (Nephrology, Hypertensiology, Endocrinology, Diabetology, and Rheumatology)Medical Faculty Mannheim of the University of HeidelbergMannheimGermany
  14. 14.Clinical Institute for Medical and Chemical Laboratory DiagnosticsMedical University of GrazGrazAustria
  15. 15.Synlab AcademySynlab Services GmbHMannheimGermany
  16. 16.Medical Clinic II, Campus GroßhadernClinic of the Ludwig Maximilian-UniversityMunichGermany
  17. 17.University Clinic for Internal Medicine ILKH Salzburg – University Clinic of the Paracelsus Medical Private UniversitySalzburgAustria
  18. 18.UFL Private University in Principality of LiechtensteinTriesenLiechtenstein
  19. 19.Dr. Pohl Endowed Professorship for Preventive Cardiology, Clinic for Internal Medicine – CardiologyUniversity Clinic Gießen and MarburgMarburgGermany
  20. 20.Charité Medical UniversityBerlinGermany
  21. 21.Evangelical Geriatrics CenterBerlinGermany
  22. 22.Department of Internal Medicine, Sankt Nikolaus Stiftshospital GmbHTeaching Hospital of the University of BonnAndernachGermany
  23. 23.Department of Internal MedicineMedical UniversityGrazAustria
  24. 24.Medical Clinic and Policlinic IUniversity ClinicWürzburgGermany
  25. 25.Preventive Medicine, Clinic und Policlinic for General and Invasive Cardiology, University Heart CenterUniversity Clinic Hamburg-EppendorfHamburgGermany