Pediatric Nephrology

, Volume 16, Issue 8, pp 672–674

Systemic lupus erythematosus and thrombotic thrombocytopenic purpura: a case and review

  • Abdullah Sakarcan
  • James Stallworth
Brief Report

DOI: 10.1007/s004670100625

Cite this article as:
Sakarcan, A. & Stallworth, J. Pediatr Nephrol (2001) 16: 672. doi:10.1007/s004670100625


Thrombotic thrombocytopenic purpura (TTP) is rare in children with systemic lupus erythematosus (SLE). We report a 15-year-old female who simultaneously presented with TTP and SLE. Kidney biopsy showed membranous nephropathy. Her condition improved with plasmapheresis, intravenous cyclophosphamide, and prednisone pulse therapy. We also reviewed the literature for this association in pediatric patients comparing presenting sequence and renal pathology with cases documented in the adult literature.

Keywords Thrombotic thrombocytopenic purpuraSystemic lupus erythematosusMembranous nephropathyPlasmapheresis

Copyright information

© IPNA - International Pediatric Nephrology Association New York, USA 2001

Authors and Affiliations

  • Abdullah Sakarcan
    • 1
  • James Stallworth
    • 1
  1. 1.Division of Pediatric Nephrology and Department of Pediatrics, University of South Carolina School of Medicine, Columbia, South Carolina, USAUS
  2. 2.Department of Pediatrics, 8 Medical Park, Columbia, SC 29203, USA e-mail: Tel.: +1-803-4347945, Fax: +1-803-4343855US