Pediatric Nephrology

, Volume 28, Issue 11, pp 2069–2078

The treatment of systemic lupus proliferative nephritis


DOI: 10.1007/s00467-012-2327-1

Cite this article as:
Punaro, M.G. Pediatr Nephrol (2013) 28: 2069. doi:10.1007/s00467-012-2327-1


Lupus nephritis is one of the most common and serious complications of systemic lupus erythematosus (SLE) in childhood affecting more than 80 % of patients. Treatment of this complication has undergone significant evolution in recent years. A series of randomized controlled trials has clarified the role of a variety of immunomodulating regimens including some novel biologic medications. This review touches on the major trials that have influenced practice and shaped current thinking about the treatment of proliferative lupus glomerulonephritis.


LupusNephritisSystemic lupus erythematosusPediatric lupusMycophenolate mofetil

Copyright information

© IPNA 2012

Authors and Affiliations

  1. 1.UT Southwestern Medical CenterDallasUSA