Pediatric Nephrology

, Volume 27, Issue 12, pp 2293–2300

Quality of life in children with end-stage renal disease based on a PedsQL ESRD module

Authors

  • Ki-Soo Park
    • Department of Preventive Medicine and Institute of Health SciencesGyeongsang National University Hospital
  • Young Ju Hwang
    • Department of PediatricsKyungpook National University Hospital
    • Department of PediatricsKyungpook National University Hospital
  • Cheol Woo Ko
    • Department of PediatricsKyungpook National University Hospital
  • Il Soo Ha
    • Department of PediatricsSeoul National University Children’s Hospital
  • Hee Gyung Kang
    • Department of PediatricsSeoul National University Children’s Hospital
  • Hae Il Cheong
    • Department of PediatricsSeoul National University Children’s Hospital
  • Young Seo Park
    • Department of PediatricsAsan Medical Center
  • Yoon Jung Lee
    • Department of PediatricsAsan Medical Center
  • Joo Hoon Lee
    • Department of PediatricsAsan Medical Center
  • Hee Yeon Cho
    • Department of PediatricsSamsung Medical Center
Original Article

DOI: 10.1007/s00467-012-2262-1

Cite this article as:
Park, K., Hwang, Y.J., Cho, M.H. et al. Pediatr Nephrol (2012) 27: 2293. doi:10.1007/s00467-012-2262-1

Abstract

Background

Health-related quality of life (HRQOL) is an essential subject for children with end-stage renal disease (ESRD) and their families.

Methods

We performed a cross-sectional investigation of HRQOL in children undergoing renal replacement therapies, such as dialysis and renal transplantation, using the 34-item Pediatric Quality of Life Inventory 3.0 End-Stage Renal Disease (PedsQL 3.0 ESRD) module. We assessed 92 ESRD patients aged 2–18 from four Korean university hospitals.

Results

The male:female ratio was 44:48, and the most common cause of ESRD was chronic glomerulonephritis. Fifty-five children were treated by dialysis, and 37 received renal transplantation. Transplant patients had better HRQOL than dialysis patients in two domains in parent proxy reports: “About my kidney disease” and “Worry.” In child self-reports, transplant patients had better HRQOL than dialysis patients in one domain: Treatment problems. However, there were no significant differences in total QOL scores between peritoneal dialysis (PD) and transplant patients in child self-reports. In addition, there were differences in the ESRD module scores between child self- and parent proxy reports. Children usually reported better QOL than their parents. Child self-reports showed significantly higher QOL scores than parent proxy reports in the domains of General fatigue, Family & peer interaction, and Worry. Children on PD self-reported a significantly higher QOL than children on hemodialysis (HD).

Conclusions

The PedsQL 3.0 ESRD module may be useful as an ESRD-specific instrument to evaluate HRQOL in children; however, a larger, longitudinal prospective study is warranted.

Keywords

Quality of lifeChildrenEnd-stage renal disease

Copyright information

© IPNA 2012