Pediatric Nephrology

, Volume 27, Issue 12, pp 2293–2300

Quality of life in children with end-stage renal disease based on a PedsQL ESRD module

  • Ki-Soo Park
  • Young Ju Hwang
  • Min Hyun Cho
  • Cheol Woo Ko
  • Il Soo Ha
  • Hee Gyung Kang
  • Hae Il Cheong
  • Young Seo Park
  • Yoon Jung Lee
  • Joo Hoon Lee
  • Hee Yeon Cho
Original Article

DOI: 10.1007/s00467-012-2262-1

Cite this article as:
Park, K., Hwang, Y.J., Cho, M.H. et al. Pediatr Nephrol (2012) 27: 2293. doi:10.1007/s00467-012-2262-1

Abstract

Background

Health-related quality of life (HRQOL) is an essential subject for children with end-stage renal disease (ESRD) and their families.

Methods

We performed a cross-sectional investigation of HRQOL in children undergoing renal replacement therapies, such as dialysis and renal transplantation, using the 34-item Pediatric Quality of Life Inventory 3.0 End-Stage Renal Disease (PedsQL 3.0 ESRD) module. We assessed 92 ESRD patients aged 2–18 from four Korean university hospitals.

Results

The male:female ratio was 44:48, and the most common cause of ESRD was chronic glomerulonephritis. Fifty-five children were treated by dialysis, and 37 received renal transplantation. Transplant patients had better HRQOL than dialysis patients in two domains in parent proxy reports: “About my kidney disease” and “Worry.” In child self-reports, transplant patients had better HRQOL than dialysis patients in one domain: Treatment problems. However, there were no significant differences in total QOL scores between peritoneal dialysis (PD) and transplant patients in child self-reports. In addition, there were differences in the ESRD module scores between child self- and parent proxy reports. Children usually reported better QOL than their parents. Child self-reports showed significantly higher QOL scores than parent proxy reports in the domains of General fatigue, Family & peer interaction, and Worry. Children on PD self-reported a significantly higher QOL than children on hemodialysis (HD).

Conclusions

The PedsQL 3.0 ESRD module may be useful as an ESRD-specific instrument to evaluate HRQOL in children; however, a larger, longitudinal prospective study is warranted.

Keywords

Quality of lifeChildrenEnd-stage renal disease

Copyright information

© IPNA 2012

Authors and Affiliations

  • Ki-Soo Park
    • 1
  • Young Ju Hwang
    • 2
  • Min Hyun Cho
    • 2
  • Cheol Woo Ko
    • 2
  • Il Soo Ha
    • 3
  • Hee Gyung Kang
    • 3
  • Hae Il Cheong
    • 3
  • Young Seo Park
    • 4
  • Yoon Jung Lee
    • 4
  • Joo Hoon Lee
    • 4
  • Hee Yeon Cho
    • 5
  1. 1.Department of Preventive Medicine and Institute of Health SciencesGyeongsang National University HospitalJinjuRepublic of Korea
  2. 2.Department of PediatricsKyungpook National University HospitalDaeguRepublic of Korea
  3. 3.Department of PediatricsSeoul National University Children’s HospitalSeoulRepublic of Korea
  4. 4.Department of PediatricsAsan Medical CenterSeoulRepublic of Korea
  5. 5.Department of PediatricsSamsung Medical CenterSeoulRepublic of Korea