Pediatric Nephrology

, Volume 27, Issue 1, pp 17–32

Hypertension in infancy: diagnosis, management and outcome

  • Janis M. Dionne
  • Carolyn L. Abitbol
  • Joseph T. Flynn

DOI: 10.1007/s00467-010-1755-z

Cite this article as:
Dionne, J.M., Abitbol, C.L. & Flynn, J.T. Pediatr Nephrol (2012) 27: 17. doi:10.1007/s00467-010-1755-z


Advances in the ability to identify, evaluate, and care for infants with hypertension, coupled with advances in the practice of Neonatology, have led to an increased awareness of hypertension in modern neonatal intensive care units. This review will present updated data on blood pressure values in neonates, with a focus on the changes that occur over the first days and weeks of life in both term and preterm infants. Optimal blood pressure measurement techniques as well as the differential diagnosis of hypertension in the neonate and older infants will be discussed. Recommendations for the optimal immediate and long-term evaluation and treatment, including potential treatment parameters, will be presented. We will also review additional information on outcome that has become available over the past decade.


Blood pressureNeonateInfantPrematurityACE inhibitorCalcium channel blockerHypertensionKidney disease

Copyright information

© IPNA 2011

Authors and Affiliations

  • Janis M. Dionne
    • 1
  • Carolyn L. Abitbol
    • 2
  • Joseph T. Flynn
    • 3
  1. 1.Division of Nephrology, Department of PediatricsUniversity of British Columbia, BC Children’s HospitalVancouverCanada
  2. 2.Division of Pediatric Nephrology, Department of PediatricsUniversity of Miami Miller School of Medicine/ Holtz Children’s HospitalMiamiUSA
  3. 3.Division of Nephrology, Seattle Children’s Hospital, Department of PediatricsUniversity of Washington School of MedicineSeattleUSA