Pediatric Nephrology

, Volume 25, Issue 3, pp 535–538

IgA nephropathy presenting with renal failure and pulmonary hemorrhage

  • Poyyapakkam Srivaths
  • Megan K. Dishop
  • Okan Elidemir
  • Karen Eldin
  • Lorna Browne
  • Ewa Elenberg
Brief Report

DOI: 10.1007/s00467-009-1382-8

Cite this article as:
Srivaths, P., Dishop, M.K., Elidemir, O. et al. Pediatr Nephrol (2010) 25: 535. doi:10.1007/s00467-009-1382-8

Abstract

Pulmonary renal syndromes are unusual, but frequently life-threatening manifestations of a distinct group of disorders in the pediatric age group. Although IgA nephropathy is a common cause of hematuria, it is an extremely rare cause of pulmonary renal syndrome, causing high mortality, and has mostly been reported in adult patients. We describe the youngest patient with this presentation reported to date, a 14-year-old male, who presented with end stage renal disease and pulmonary hemorrhage and was found to have IgA nephropathy by renal biopsy and pulmonary capillaritis by open lung biopsy. His lung disease was successfully treated with immunosuppressive medications. Despite this being a rare manifestation of IgA nephropathy, clinicians need to be aware of this presentation as it is potentially fatal, but amenable to aggressive immunosuppression.

Keywords

End stage renal diseaseHematuriaIgA nephropathyPulmonary capillaritisPulmonary hemorrhage

Copyright information

© IPNA 2009

Authors and Affiliations

  • Poyyapakkam Srivaths
    • 1
  • Megan K. Dishop
    • 2
  • Okan Elidemir
    • 3
  • Karen Eldin
    • 2
  • Lorna Browne
    • 4
  • Ewa Elenberg
    • 1
  1. 1.Department of Pediatrics Renal SectionBaylor College of MedicineHoustonUSA
  2. 2.Department of PathologyBaylor College of MedicineHoustonUSA
  3. 3.Department of Pediatrics Pulmonary SectionBaylor College of MedicineHoustonUSA
  4. 4.Department of RadiologyBaylor College of MedicineHoustonUSA