Pediatric Nephrology

, Volume 25, Issue 1, pp 37–47

Official positions of the International Society for Clinical Densitometry (ISCD) on DXA evaluation in children and adolescents

  • Maria Luisa Bianchi
  • Sanford Baim
  • Nick J. Bishop
  • Catherine M. Gordon
  • Didier B. Hans
  • Craig B. Langman
  • Mary B. Leonard
  • Heidi J. Kalkwarf
Conference Report

DOI: 10.1007/s00467-009-1249-z

Cite this article as:
Bianchi, M.L., Baim, S., Bishop, N.J. et al. Pediatr Nephrol (2010) 25: 37. doi:10.1007/s00467-009-1249-z

Abstract

Dual-energy X-ray absorptiometry (DXA) is the most widely used technical instrument for evaluating bone mineral content (BMC) and density (BMD) in patients of all ages. However, its use in pediatric patients, during growth and development, poses a much more complex problem in terms of both the technical aspects and the interpretation of the results. For the adults population, there is a well-defined term of reference: the peak value of BMD attained by young healthy subjects at the end of skeletal growth. During childhood and adolescence, the comparison can be made only with healthy subjects of the same age, sex and ethnicity, but the situation is compounded by the wide individual variation in the process of skeletal growth (pubertal development, hormone action, body size and bone size). The International Society for Clinical Densitometry (ISCD) organized a Pediatric Position Development Conference to discuss the specific problems of bone densitometry in growing subjects (9–19 years of age) and to provide essential recommendations for its clinical use.

Keywords

AdolescentsBone mineral densityDXAChildrenFracturesOsteoporosis

Copyright information

© IPNA 2009

Authors and Affiliations

  • Maria Luisa Bianchi
    • 1
  • Sanford Baim
    • 2
  • Nick J. Bishop
    • 3
  • Catherine M. Gordon
    • 4
  • Didier B. Hans
    • 5
  • Craig B. Langman
    • 6
    • 7
  • Mary B. Leonard
    • 8
  • Heidi J. Kalkwarf
    • 9
  1. 1.Bone Metabolism UnitIstituto Auxologico Italiano (IRCCS)MilanItaly
  2. 2.Colorado Center for Bone ResearchLakewoodUSA
  3. 3.Sheffield Children’s NHS Foundation TrustSheffield UniversitySheffieldUK
  4. 4.Children’s Hospital BostonBostonUSA
  5. 5.Center of Bone DiseasesLausanne University HospitalLausanneSwitzerland
  6. 6.Feinberg School of MedicineNorthwestern UniversityChicagoUSA
  7. 7.Division of Kidney DiseasesChildren’s Memorial HospitalChicagoUSA
  8. 8.Children’s Hospital of PhiladelphiaPhiladelphiaUSA
  9. 9.Cincinnati Children’s Hospital Medical CenterCincinnatiUSA