Pediatric Nephrology

, Volume 24, Issue 8, pp 1561–1568

Quality of life of adolescents with end-stage renal disease and kidney transplant

Authors

  • Isolina Riaño-Galán
    • Division of PaediatricsHospital San Agustín
    • Division of Paediatric NephrologyHospital Universitario Central de Asturias
  • Luis Rajmil
    • Agència d’Avaluació de Tecnologia i Recerca Mèdiques (AATRM)Institut Municipal d’Investigació Mèdica (IMIM) and CIBER en Epidemiología y Salud Pública (CIBERESP)
  • Gema Ariceta
    • Division of Paediatric NephrologyHospital Clínico de Santiago
  • Mercedes Navarro
    • Division of Paediatric NephrologyHospital Universitario Infantil La Paz
  • Cesar Loris
    • Division of Paediatric NephrologyHospital Miguel Servet
  • Alfredo Vallo
    • Division of Paediatric NephrologyHospital Cruces
Original Article

DOI: 10.1007/s00467-009-1175-0

Cite this article as:
Riaño-Galán, I., Málaga, S., Rajmil, L. et al. Pediatr Nephrol (2009) 24: 1561. doi:10.1007/s00467-009-1175-0

Abstract

The health-related quality of life (HRQOL) of adolescents with end-stage renal disease (ESRD) is an important marker of disease burden. Our aims were to investigate HRQOL in a group of children and adolescents with ESRD and to compare them with the reference population norms. Ours was a cross-sectional study of 81 patients aged 10 years to 21 years with ESRD (68 with kidney transplants and 13 on dialysis) at five Spanish paediatric nephrology centres. HRQOL was investigated with the Spanish version of the child health and illness profile, adolescent edition (CHIP-AE). Clinical variables such as underlying diagnosis, number of rejection episodes, pre-emptive transplantation, anaemia and height were also analysed. No differences were found between patients with kidney transplants and their healthy peers in any domain or sub-domain of CHIP-AE. The group on dialysis scored lower than healthy controls and patients with transplants for satisfaction with health. Discomfort was higher in patients with transplants who had suffered one rejection episode. Physical discomfort was increased in anaemic patients with transplants. Short patients scored less in the satisfaction domain, with lower self-esteem and lower satisfaction with health. Adolescents with kidney transplants had better satisfaction with health than the group on dialysis, which matched the level of a healthy population. Further long-term prospective research is warranted.

Keywords

DialysisEnd-stage renal diseaseHealth-related quality of lifeKidney transplantPaediatricTeenagers

Copyright information

© IPNA 2009