Pediatric Nephrology

, Volume 23, Issue 10, pp 1889–1891

A sporadic case of paraganglioma undetected by urine metabolite screening

  • Detlef Bockenhauer
  • Lesley Rees
  • Hartmut Neumann
  • Ying Foo
Brief Report

DOI: 10.1007/s00467-008-0841-y

Cite this article as:
Bockenhauer, D., Rees, L., Neumann, H. et al. Pediatr Nephrol (2008) 23: 1889. doi:10.1007/s00467-008-0841-y

Abstract

Phaeochromocytoma is a rare cause of hypertension in children, but important to be recognised, as hypertension can be severe and surgery is often curative. Here, we report on a 7-year-old boy with a phaeochromocytoma, who had normal levels of commonly assayed catecholamine metabolites in the urine. Postoperatively, the patient developed renal vein thrombosis. Appropriate screening tests for phaeochromocytomas, peri-operative management, and the high incidence of an underlying genetic basis, even in sporadic cases, are discussed.

Keywords

Paraganglioma Phaeochromocytoma Catecholamine Vanillylmandelic acid Homovanillic acid Metanephrines Hypertension 

Copyright information

© IPNA 2008

Authors and Affiliations

  • Detlef Bockenhauer
    • 1
  • Lesley Rees
    • 1
  • Hartmut Neumann
    • 2
  • Ying Foo
    • 3
  1. 1.Department of NephrologyGreat Ormond Street Hospital for Children NHS TrustLondonUK
  2. 2.Division of Nephrology and HypertensionAlbert-Ludwigs University of FreiburgFreiburgGermany
  3. 3.Chemical PathologyGreat Ormond Street Hospital for Children NHS TrustLondonUK

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