Original Article

Pediatric Nephrology

, Volume 23, Issue 8, pp 1347-1354

First online:

Outcome after renal transplantation. Part II: Quality of life and psychosocial adjustment

  • Jutta FalgerAffiliated withNephrology Unit, University Children’s Hospital
  • , Markus A. LandoltAffiliated withDepartment of Psychosomatics and Psychiatry, University Children’s Hospital
  • , Bea LatalAffiliated withChild Development Centre, University Children’s Hospital
  • , Eva M. RüthAffiliated withNephrology Unit, University Children’s Hospital
  • , Thomas J. NeuhausAffiliated withNephrology Unit, University Children’s Hospital
  • , Guido F. LaubeAffiliated withNephrology Unit, University Children’s Hospital Email author 

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Knowledge of health-related quality of life (QOL) and psychosocial adjustment (PA) in children after renal transplantation (RTPL) is limited. QOL and PA were evaluated by standardized tests in patients after RTPL. Thirty-seven children of median age 14.5 years (range 6.5–17 years) were investigated a mean 4.5 years (range 0.5–12.8 years) after RTPL. Child- and parent-rated QOL was evaluated with the Child Quality of life Questionnaire of The Netherlands Organization for Applied Scientific Research Academical Medical Centre (TNO-AZL). PA was assessed by the Child Behaviour Checklist (CBCL) providing parental reports of a child’s behaviour. In patients’ self-ratings, the QOL dimension physical complaints (P < 0.0005) scored significantly better than that of healthy controls, whereas the dimension positive emotional functioning was impaired (P = 0.02). Parents rated motor functioning (P = 0.002), autonomy (P = 0.01), cognition (P = 0.04) and positive emotions (P < 0.0005) as significantly impaired. Parents also assessed PA significantly (P = 0.02) impaired with regard to internalizing behaviour. Dialysis duration, young age at RTPL, living-related donation, steroid treatment, adverse family relationships and maternal distress had a significantly negative impact on QOL and PA (P < 0.05). Patients rated QOL higher than did healthy controls. Parents evaluated their children’s QOL and PA more pessimistically than did the patients themselves. Both illness-related variables and family environment played an important role.


Renal transplantation Outcome Health-related quality of life Psychosocial adjustment