Pediatric Nephrology

, Volume 23, Issue 8, pp 1347–1354

Outcome after renal transplantation. Part II: Quality of life and psychosocial adjustment


  • Jutta Falger
    • Nephrology UnitUniversity Children’s Hospital
  • Markus A. Landolt
    • Department of Psychosomatics and PsychiatryUniversity Children’s Hospital
  • Bea Latal
    • Child Development CentreUniversity Children’s Hospital
  • Eva M. Rüth
    • Nephrology UnitUniversity Children’s Hospital
  • Thomas J. Neuhaus
    • Nephrology UnitUniversity Children’s Hospital
    • Nephrology UnitUniversity Children’s Hospital
Original Article

DOI: 10.1007/s00467-008-0798-x

Cite this article as:
Falger, J., Landolt, M.A., Latal, B. et al. Pediatr Nephrol (2008) 23: 1347. doi:10.1007/s00467-008-0798-x


Knowledge of health-related quality of life (QOL) and psychosocial adjustment (PA) in children after renal transplantation (RTPL) is limited. QOL and PA were evaluated by standardized tests in patients after RTPL. Thirty-seven children of median age 14.5 years (range 6.5–17 years) were investigated a mean 4.5 years (range 0.5–12.8 years) after RTPL. Child- and parent-rated QOL was evaluated with the Child Quality of life Questionnaire of The Netherlands Organization for Applied Scientific Research Academical Medical Centre (TNO-AZL). PA was assessed by the Child Behaviour Checklist (CBCL) providing parental reports of a child’s behaviour. In patients’ self-ratings, the QOL dimension physical complaints (P < 0.0005) scored significantly better than that of healthy controls, whereas the dimension positive emotional functioning was impaired (P = 0.02). Parents rated motor functioning (P = 0.002), autonomy (P = 0.01), cognition (P = 0.04) and positive emotions (P < 0.0005) as significantly impaired. Parents also assessed PA significantly (P = 0.02) impaired with regard to internalizing behaviour. Dialysis duration, young age at RTPL, living-related donation, steroid treatment, adverse family relationships and maternal distress had a significantly negative impact on QOL and PA (P < 0.05). Patients rated QOL higher than did healthy controls. Parents evaluated their children’s QOL and PA more pessimistically than did the patients themselves. Both illness-related variables and family environment played an important role.


Renal transplantationOutcomeHealth-related quality of lifePsychosocial adjustment

Copyright information

© IPNA 2008