Pediatric Nephrology

, Volume 21, Issue 7, pp 1034–1036

Nephrotoxicity in a child with perinatal HIV on tenofovir, didanosine and lopinavir/ritonavir

  • Sabiha Hussain
  • Abeer Khayat
  • Asad Tolaymat
  • Mobeen H. Rathore
Brief Report

DOI: 10.1007/s00467-006-0109-3

Cite this article as:
Hussain, S., Khayat, A., Tolaymat, A. et al. Pediatr Nephrol (2006) 21: 1034. doi:10.1007/s00467-006-0109-3

Abstract

Tenofovir-related tubule damage characterized by Fanconi syndrome, renal insufficiency and nephrogenic diabetes insipidus has been reported in the adult HIV-infected population. To our knowledge there has been no reported case of such complications in the pediatric population. We report the case of a 12-year-old perinatally HIV-infected African–American girl who developed nephrogenic diabetes insipidus, renal insufficiency and Fanconi-like syndrome while taking tenofovir (Viread) in combination with lopinavir–ritonavir (Kaletra) and didanosine (Videx).

Keywords

Fanconi syndromeRenal insufficiencyNephrogenic diabetes insipidusHIVTenofovir

Copyright information

© IPNA 2006

Authors and Affiliations

  • Sabiha Hussain
    • 1
  • Abeer Khayat
    • 1
  • Asad Tolaymat
    • 4
  • Mobeen H. Rathore
    • 1
    • 2
    • 3
  1. 1.Pediatric Infectious Diseases and ImmunologyUniversity of FloridaJacksonvilleUSA
  2. 2.Wolfson Children’s HospitalJacksonvilleUSA
  3. 3.JacksonvilleUSA
  4. 4.Department of PediatricsUniversity of FloridaJacksonvilleUSA