, Volume 18, Issue 8, pp 805-809,
Open Access This content is freely available online to anyone, anywhere at any time.
Date: 15 May 2003

The management of anemia in pediatric peritoneal dialysis patients

Abstract

Anemia is common in chronic renal failure. Guidelines for the diagnosis and treatment of anemia in adult patients are available. With respect to the diagnosis and treatment in children on peritoneal dialysis, the European Pediatric Peritoneal Dialysis Working Group (EPPWG) has produced guidelines. After a thorough diagnostic work-up, treatment should aim for a target hemoglobin concentration of at least 11 g/l. This can be accomplished by the administration of erythropoietin and iron preparations. Although there is sufficient evidence to advocate the intraperitoneal administration of erythropoietin, most pediatric nephrologists still apply erythropoietin by the subcutaneous route. Iron should preferably be prescribed as an oral preparation. Sufficient attention has to be paid to the nutritional intake in these children. There is no place for carnitine supplementation in the treatment of anemia in pediatric peritoneal dialysis patients.

The European Pediatric Peritoneal Dialysis Working Group comprises:
A. Edefonti, I Clinici di Perfezionamento, Milan, Italy
M. Fischbach, Hôpital de Hautepierre, Strasbourg, France
G. Klaus, University of Marburg, Marburg, Germany
K. Rönnholm, University of Helsinki, Helsinki, Finland
F. Schaefer, University of Heidelberg, Heidelberg, Germany
E. Simkova, University Hospital Motol, Prague, Czech Republic
D. Stefanidis, A&P Kyriakou Children's Hospital, Athens, Greece
V. Strazdins, University Hospital for Children, Riga, Latvia
J. Vande Walle, University of Ghent, Ghent, Belgium
A. Watson, Nottingham City Hospital, Nottingham, United Kingdom
A. Zurowska, University of Gdansk, Gdansk, Poland