Surgical Endoscopy

, Volume 28, Issue 5, pp 1634–1640

Risk of developing metachronous colon neoplasm after polypectomy: comparison of one-stage versus two-stage polypectomy

  • Soo-Kyung Park
  • Jong Wook Kim
  • Sang Hyoung Park
  • Dong-Hoon Yang
  • Kee Wook Jung
  • Kyung Jo Kim
  • Byong Duk Ye
  • Seung-Jae Myung
  • Suk-Kyun Yang
  • Jin-Ho Kim
  • Jeong-Sik Byeon
Article

DOI: 10.1007/s00464-013-3363-z

Cite this article as:
Park, S., Kim, J.W., Park, S.H. et al. Surg Endosc (2014) 28: 1634. doi:10.1007/s00464-013-3363-z

Abstract

Background

The impact of one-stage polypectomy (removal of all neoplasms during diagnostic colonoscopy) versus two-stage polypectomy (removal of all neoplasms during therapeutic colonoscopy following the initial diagnostic colonoscopy) on the development of metachronous neoplasms is poorly understood. Our aim was to compare the effects of one- versus two-stage polypectomy on the development of metachronous neoplasms

Methods

We retrospectively reviewed the medical records of 249 patients in a tertiary center who underwent one-stage polypectomy, which was followed by one or more surveillance colonoscopy. The development of metachronous neoplasm in this group was compared with that of an age- and sex-matched two-stage polypectomy group consisting of 498 patients

Results

In total, 346 (46.3 %) patients developed any metachronous neoplasm and 29 (3.9 %) patients developed advanced metachronous neoplasm. The 5 years cumulative incidences of any and advanced metachronous neoplasm were 46.2 and 5.0 %, respectively, in the one-stage group, which are not significantly different from the rates of 50.7 and 3.3 % in the two-stage group (p = 0.94 and 0.30, respectively). The only significant risk factor for developing any metachronous neoplasm was ≥3 neoplasms at the baseline polypectomy [hazard ratio (HR) 1.75; 95 % confidence interval (CI) 1.41–2.17; p < 0.001]. The only significant risk factor for developing advanced metachronous neoplasm was advanced neoplasm at the baseline polypectomy (HR 2.37; 95 % CI 1.16–4.84; p = 0.01). One- and two-stage polypectomy did not affect the development rates of metachronous neoplasm

Conclusions

The risks of developing metachronous neoplasm may be similar following one- and two-stage polypectomy.

Keywords

PolypectomyColonNeoplasms

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Soo-Kyung Park
    • 1
  • Jong Wook Kim
    • 2
  • Sang Hyoung Park
    • 1
  • Dong-Hoon Yang
    • 1
  • Kee Wook Jung
    • 1
  • Kyung Jo Kim
    • 1
  • Byong Duk Ye
    • 1
  • Seung-Jae Myung
    • 1
  • Suk-Kyun Yang
    • 1
  • Jin-Ho Kim
    • 1
  • Jeong-Sik Byeon
    • 1
  1. 1.Department of Gastroenterology and Inflammatory Bowel Disease CenterAsan Medical Center, University of Ulsan College of MedicineSeoulKorea
  2. 2.Division of Gastroenterology, Department of Internal MedicineInje University Ilsan Paik HospitalGoyangKorea