Dysphagia

, Volume 22, Issue 1, pp 44–48

Eosinophilic Esophagitis in Infants and Toddlers

  • Scott P. Pentiuk
  • Claire Kane Miller
  • Ajay Kaul
Article

DOI: 10.1007/s00455-006-9040-9

Cite this article as:
Pentiuk, S.P., Miller, C.K. & Kaul, A. Dysphagia (2007) 22: 44. doi:10.1007/s00455-006-9040-9

Abstract

Feeding refusal is often described in conjunction with the diagnosis of eosinophilic esophagitis (EE) in pediatric patients; however, there are little data regarding the specific clinical manifestations and effective management of this condition in very young children. The aim of this study was to evaluate the presentation of EE in infants and toddlers referred to the Interdisciplinary Feeding Team Clinic of a tertiary referral center and to document responses to treatment. Database matching was performed (from January 2000 to June 2003) to identify infants and toddlers diagnosed with EE who had been referred to the Interdisciplinary Feeding Team Clinic. Endoscopic features required for a diagnosis of EE included esophageal mucosal furrowing, erythema, exudates, or decreased vascular markings. Histologic features of EE were more than 24 eosinophils per high-power field (HPF), thickening of basal cell layer, and papillary (rete peg) lengthening or elongation. All study patients were treated with a combination of proton pump inhibitors (PPI) and fluticasone (swallowed). In addition, elemental diet was instituted in those documented to have a food allergy. Treatment success was defined by an improved oral intake, adequate weight gain, and improved endoscopic and histologic findings at 3–6-month followup. A total of 15 subjects [mean age = 19.9 months (SD = 9.7 months)] who fulfilled the entry criteria during the study period were identified. All 15 children had documented endoscopic improvement and 14/15 children had histologic resolution of EE after therapy. In 13 of the 15 children, this translated to clinical improvement as well.

Keywords

Eosinophilic esophagitisOral aversionPediatricsDeglutitionDeglutition disorders

Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • Scott P. Pentiuk
    • 1
    • 2
    • 3
  • Claire Kane Miller
    • 1
    • 2
    • 3
  • Ajay Kaul
    • 1
    • 2
    • 3
    • 4
  1. 1.Department of PediatricsCincinnati Children’s Hospital Medical CenterCincinnatiUSA
  2. 2.Department of Speech PathologyCincinnati Children’s Hospital Medical CenterCincinnatiUSA
  3. 3.Department of Gastroenterology, Hepatology, and NutritionCincinnati Children’s Hospital Medical CenterCincinnatiUSA
  4. 4.Department of Gastroenterology, Hepatology, and NutritionCincinnati Children’s Hospital Medical CenterCincinnatiUSA