Human Genetics

, Volume 102, Issue 2, pp 138–140

Inheritance of chronic tension-type headache investigated by complex segregation analysis

Authors

  • Michael Bjørn Russell
    • Department of Neurology, Glostrup Hospital, University of Copenhagen, DK-2600 Glostrup, Copenhagen, Denmark Fax: +45-43-23-39-26
  • Lennart Iselius
    • Department of Surgery, Karolinska Hospital, Stockholm, Sweden
  • Steen Østergaard
    • Department of Neurology, Glostrup Hospital, University of Copenhagen, DK-2600 Glostrup, Copenhagen, Denmark Fax: +45-43-23-39-26
  • Jes Olesen
    • Department of Neurology, Glostrup Hospital, University of Copenhagen, DK-2600 Glostrup, Copenhagen, Denmark Fax: +45-43-23-39-26
Original investigation

DOI: 10.1007/s004390050666

Cite this article as:
Russell, M., Iselius, L., Østergaard, S. et al. Hum Genet (1998) 102: 138. doi:10.1007/s004390050666

Abstract

We investigated the mode of inheritance of chronic tension-type headache in 122 families. The probands were from the Copenhagen Headache Clinic, Denmark. The criteria of the International Headache Society were used. The patterns of segregation of chronic tension-type headache were assessed by complex segregation analysis performed with the computer program POINTER. Of the 122 probands with chronic tension-type headache, 56 had 71 first-degree relatives with chronic tension-type headache. The complex segregation analysis indicates that chronic tension-type headache has multifactorial inheritance.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1998