Human Genetics

, Volume 98, Issue 5, pp 518–521

Dombrock blood group (DO): assignment to chromosome 12p

  • H. Eiberg
  • Jan Mohr
Original investigation

DOI: 10.1007/s004390050251

Cite this article as:
Eiberg, H. & Mohr, J. Hum Genet (1996) 98: 518. doi:10.1007/s004390050251

Abstract

The Dombrock blood group system (DO) is a common polymorphism in Caucasians, represented by two red cell antigen alleles. In a linkage study in our family material of 832 families from the Copenhagen area, we found a strong indication of tight linkage with the two flanking DNA polymorphisms D12S358 (z = 7.66; at θM = 0.001, θF = 0.031) and D12S364 (z = 8.53; at θM = 0.068, θF = 0.031). DO is assigned to the region 12p13.2– 12p12.1 by physically localised markers.

Copyright information

© Springer-Verlag Berlin Heidelberg 1996

Authors and Affiliations

  • H. Eiberg
    • 1
  • Jan Mohr
    • 1
  1. 1.Institute of Medical Biochemistry and Genetics, Department of Genetics, Building 24.4, Blegdamsvej 3, DK-2200 Copenhagen N, Denmark Tel.: +45-35-32-78-29; Fax: +45-31-39-33-73; e-mail he@rclink.imbg.ku.dkDK