Dombrock blood group (DO): assignment to chromosome 12p
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- Eiberg, H. & Mohr, J. Hum Genet (1996) 98: 518. doi:10.1007/s004390050251
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The Dombrock blood group system (DO) is a common polymorphism in Caucasians, represented by two red cell antigen alleles. In a linkage study in our family material of 832 families from the Copenhagen area, we found a strong indication of tight linkage with the two flanking DNA polymorphisms D12S358 (z = 7.66; at θM = 0.001, θF = 0.031) and D12S364 (z = 8.53; at θM = 0.068, θF = 0.031). DO is assigned to the region 12p13.2– 12p12.1 by physically localised markers.