Molecular and General Genetics MGG

, Volume 262, Issue 4, pp 618–622

HeT-A telomere-specific retrotransposons in the centric heterochromatin of Drosophila melanogaster chromosome 3

Authors

  • A. Losada
    • Centro de Biología Molecular “Severo Ochoa” (CSIC-UAM), 28049 Madrid, Spain E-mail: avillasante@cbm.uam.es Tel.: +34-91-3974692; Fax: +34-91-3974799
  • M. Agudo
    • Centro de Biología Molecular “Severo Ochoa” (CSIC-UAM), 28049 Madrid, Spain E-mail: avillasante@cbm.uam.es Tel.: +34-91-3974692; Fax: +34-91-3974799
  • J. P. Abad
    • Centro de Biología Molecular “Severo Ochoa” (CSIC-UAM), 28049 Madrid, Spain E-mail: avillasante@cbm.uam.es Tel.: +34-91-3974692; Fax: +34-91-3974799
  • A. Villasante
    • Centro de Biología Molecular “Severo Ochoa” (CSIC-UAM), 28049 Madrid, Spain E-mail: avillasante@cbm.uam.es Tel.: +34-91-3974692; Fax: +34-91-3974799
ORIGINAL PAPER

DOI: 10.1007/s004380051124

Cite this article as:
Losada, A., Agudo, M., Abad, J. et al. Mol Gen Genet (1999) 262: 618. doi:10.1007/s004380051124

Abstract

We have isolated two yeast artificial chromosome (YAC) clones from Drosophila melanogaster that contain a small amount of dodeca satellite (a satellite DNA located in the centromeric region of chromosome 3) and sequences homologous to the telomeric retrotransposon HeT-A. Using these YACs as probes for fluorescence in situ hybridization to mitotic chromosomes, we have localized these HeT-A elements to the centric heterochromatin of chromosome 3, at region h55. The possible origin of these telomeric elements in a centromeric position is discussed.

Key words Telomeric retrotransposonsHeT-A elementsCentric heterochromatinDrosophila

Copyright information

© Springer-Verlag Berlin Heidelberg 1999