Parasitology Research

, Volume 82, Issue 1, pp 90–91

Glycoprotein A is the immunodominant antigen of pneumocystis carinii in mice following immunization

  • Francis Gigliotti
  • Tera McCool
Short Communication

DOI: 10.1007/s004360050075

Cite this article as:
Gigliotti, F. & McCool, T. Parasitol Res (1996) 82: 90. doi:10.1007/s004360050075


A rapid and simple dual enzyme-linked immunosorbent assay was developed to quantitate the relative frequency of monoclonal antibodies produced against Pneumocystis carinii glycoprotein A (gpA) or other antigens of P. carinii after immunization with whole organisms. In BALB/cj mice, P. carinii gpA was clearly the immunodominant antigen, with a quarter of all hybridomas secreting antibody directed against this molecule.

Copyright information

© Springer-Verlag 1996

Authors and Affiliations

  • Francis Gigliotti
    • 1
  • Tera McCool
    • 2
  1. 1.University of Rochester Medical CenterRochesterUSA
  2. 2.University of RochesterRochesterUSA