Glycoprotein A is the immunodominant antigen of pneumocystis carinii in mice following immunization
- Cite this article as:
- Gigliotti, F. & McCool, T. Parasitol Res (1996) 82: 90. doi:10.1007/s004360050075
- 14 Views
A rapid and simple dual enzyme-linked immunosorbent assay was developed to quantitate the relative frequency of monoclonal antibodies produced against Pneumocystis carinii glycoprotein A (gpA) or other antigens of P. carinii after immunization with whole organisms. In BALB/cj mice, P. carinii gpA was clearly the immunodominant antigen, with a quarter of all hybridomas secreting antibody directed against this molecule.