Parasitology Research

, Volume 111, Issue 1, pp 1–6

From methylene blue to chloroquine: a brief review of the development of an antimalarial therapy

  • Kristine Krafts
  • Ernst Hempelmann
  • Agnieszka Skórska-Stania

DOI: 10.1007/s00436-012-2886-x

Cite this article as:
Krafts, K., Hempelmann, E. & Skórska-Stania, A. Parasitol Res (2012) 111: 1. doi:10.1007/s00436-012-2886-x


Malarial treatment is widely and readily available today. However, there was a time in the not-so-distant past when malaria was a deadly disease with no known cause or cure. In this article, we trace the origins of an antimalarial therapy from the discovery of the nature of the malarial parasite through the development of chloroquine. We dedicate this article to Johann “Hans” Andersag, the scientist who developed chloroquine, on the 110th anniversary of his birth, 16 February 1902.

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Kristine Krafts
    • 1
  • Ernst Hempelmann
    • 2
  • Agnieszka Skórska-Stania
    • 3
  1. 1.Department of PathologyUniversity of Minnesota School of MedicineDuluthUSA
  2. 2.Department of PharmacologyWitwatersrand UniversityJohannesburgSouth Africa
  3. 3.Department of Crystal Physics and Crystal Chemistry, Faculty of ChemistryJagiellonian UniversityKrakówPoland