Parasitology Research

, Volume 109, Issue 3, pp 959–962

Mucosal Leishmania infantum infection

  • Joachim Richter
  • Ingrid Hanus
  • Dieter Häussinger
  • Thomas Löscher
  • Gundel Harms
Short Communication

DOI: 10.1007/s00436-011-2356-x

Cite this article as:
Richter, J., Hanus, I., Häussinger, D. et al. Parasitol Res (2011) 109: 959. doi:10.1007/s00436-011-2356-x

Abstract

Mucosal leishmaniasis is a well-known clinical manifestation of infections caused by species belonging to the Leishmania (Viannia) subgenus in Central and South America but not of Leishmania species endemic in the so-called Old World. We report on three cases of mucosal leishmaniasis caused by Leishmania (Leishmania) infantum contracted in southern Europe. Two patients were immunocompromised; one patient had no underlying condition. Lesions were located in the oral mucosa, oesophagus and nose. All lesions relapsed under standard treatment with liposomal amphotericin B. A cure was achieved after secondary and extended treatment with liposomal amphotericin B or miltefosine. Mucosal leishmaniasis contracted in southern Europe has to be considered in the differential diagnosis of lesions in the naso–buccal–oesophageal mucosa and may occur in previously healthy persons.

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Joachim Richter
    • 1
  • Ingrid Hanus
    • 2
  • Dieter Häussinger
    • 1
  • Thomas Löscher
    • 2
  • Gundel Harms
    • 3
  1. 1.Tropical Medicine Unit, Clinics for Gastroenterology, Hepatology and Infectious Diseases, University Clinics DüsseldorfHeinrich-Heine-University DüsseldorfDüsseldorfGermany
  2. 2.Department of Infectious Diseases and Tropical MedicineUniversity of MunichMunichGermany
  3. 3.Institute of Tropical Medicine and International HealthCharité-Universitätsmedizin BerlinBerlinGermany