Short Communication

Parasitology Research

, Volume 103, Issue 3, pp 713-715

Skin prick test of Kudoa sp. antigens in patients with gastrointestinal and/or allergic symptoms related to fish ingestion

  • Gonzalo Martínez de VelascoAffiliated withDepartamento de Parasitología, Facultad de Farmacia, Universidad Complutense
  • , Marta RoderoAffiliated withDepartamento de Parasitología, Facultad de Farmacia, Universidad Complutense
  • , Carmen CuéllarAffiliated withDepartamento de Parasitología, Facultad de Farmacia, Universidad Complutense Email author 
  • , Tomás ChivatoAffiliated withImmunology and Allergy Service, Hospital del Aire
  • , José María MateosAffiliated withImmunology and Allergy Service, Hospital del Aire
  • , Rafael LagunaAffiliated withImmunology and Allergy Service, Hospital del Aire

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Abstract

A majority of Kudoa spp. infects the somatic muscle of fish establishing cysts. Previously, elevated humoral responses were detected in BALB/c mice immunised with Kudoa sp. pseudocyst extracts and in BALB/c mice orally inoculated with Kudoa sp. pseudocysts, as well as the presence of anti-Kudoa sp. antibodies in human sera by enzyme-linked immunosorbent assay. The objective of this work was to test Kudoa sp. pseudocyst extracts by the skin prick test. Fifteen patients with gastroallergic and/or allergic symptoms related to fish ingestion were examined. Kudoa sp. pseudocyst extracts were administered (1 mg/ml) on the volar forearm skin. Four of the 15 selected patients were positive to Kudoa sp. extracts. The saline solution negative control did not induce any reaction.