Plasmodium malariae infection in spite of previous anti-malarial medication
- First Online:
- Cite this article as:
- Müller-Stöver, I., Verweij, J.J., Hoppenheit, B. et al. Parasitol Res (2008) 102: 547. doi:10.1007/s00436-007-0804-4
- 128 Downloads
Plasmodium malariae is regarded as usually being susceptible to all anti-malarials whether applied for prophylaxis or treatment. We report on three cases of P. malariae infection which occurred 12–14 weeks after anti-malarial chemoprophylaxis or treatment with mefloquine or atovaquone/proguanil. The most likely explanation for the failure of mefloquine and atovaquone/proguanil to prevent quartan malaria occurring some months later is the insufficient effect on the particularly long-lasting pre-erythrocytic development stages of P. malariae.