Parasitology Research

, Volume 96, Issue 4, pp 242–246

Screening for cystic echinococcosis in an endemic region of Peru using portable ultrasonography and the enzyme-linked immunoelectrotransfer blot (EITB) assay

  • Pedro L. Moro
  • Hector H. Garcia
  • Armando E. Gonzales
  • Juan J. Bonilla
  • Manuela Verastegui
  • Robert H. GilmanMD
Original Paper

DOI: 10.1007/s00436-005-1350-6

Cite this article as:
Moro, P.L., Garcia, H.H., Gonzales, A.E. et al. Parasitol Res (2005) 96: 242. doi:10.1007/s00436-005-1350-6

Abstract

Cystic echinococcosis (CE) caused by the larval form of Echinococcus granulosus is a major public health problem in sheep-raising regions of the World. This study compared portable ultrasound with the enzyme-linked immunoelectrotransfer blot (EITB) assay as screening methods to estimate the prevalence of human CE in a remote village in the Peruvian Andes. Three hundred eighty-nine villagers were examined by portable ultrasound and blood samples were drawn by venipuncture. Sera were collected and tested for antibodies against CE using an EITB assay. Cystic lesions were classified based on their ultrasound morphologic characteristics. The prevalence of human CE using portable ultrasound and the EITB assay were 4.9% and 2.6%, respectively. Fifty-three percent of subjects with CE were EITB positive. Portable ultrasound was well received by the community, augmented CE detection and allowed a faster estimate of human infection than the EITB assay.

Keywords

Cystic echinococcosisUltrasonographyEnzyme-linked immunoelectrotransfer blotEpidemiologyPeru

Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  • Pedro L. Moro
    • 1
  • Hector H. Garcia
    • 2
  • Armando E. Gonzales
    • 3
  • Juan J. Bonilla
    • 4
  • Manuela Verastegui
    • 2
  • Robert H. GilmanMD
    • 5
  1. 1.National Immunization ProgramCenters for Disease Control and PreventionAtlantaUSA
  2. 2.Department of MicrobiologyUniversidad Peruana Cayetano HerediaSMPPeru
  3. 3.School of Veterinary MedicineUniversidad Nacional Mayor de San MarcosSalamanca de MonterricoPeru
  4. 4.Department of GastroenterologyPoliclínico Peruano-JaponesJesus MariaPeru
  5. 5.Department of International HealthJohns Hopkins University School of Hygiene and Public HealthBaltimoreUSA