Parasitology Research

, Volume 93, Issue 4, pp 322–327

No change in parasite genotype during single episodes of Plasmodium falciparum malaria in Gabonese children

Authors

  • Michel A. Missinou
    • Department of Parasitology, Institute of Tropical MedicineUniversity of Tübingen
    • Medical Research UnitAlbert Schweitzer Hospital
  • Jürgen F. J. Kun
    • Department of Parasitology, Institute of Tropical MedicineUniversity of Tübingen
    • Department of Parasitology, Institute of Tropical MedicineUniversity of Tübingen
    • Medical Research UnitAlbert Schweitzer Hospital
Original Paper

DOI: 10.1007/s00436-004-1137-1

Cite this article as:
Missinou, M.A., Kun, J.F.J. & Kremsner, P.G. Parasitol Res (2004) 93: 322. doi:10.1007/s00436-004-1137-1

Abstract

Patients living in endemic areas can carry a mixture of Plasmodium falciparum genotypes. To investigate the genetic composition of parasite genotypes in malaria patients during the acute phase of the infection, we performed close follow-ups of 17 Gabonese pediatric patients aged 2–7 years. Capillary blood samples were taken on admission and every 4–6 h after the start of quinine therapy. Merozoite surface protein 2 (MSP2) genotypes were used to assess the parasites’ genetic characteristics in each sample. We found that each patient carried parasites with the same genotypic pattern throughout the infection.

Copyright information

© Springer-Verlag 2004