Short Communication

Parasitology Research

, Volume 88, Issue 12, pp 1090-1092

First online:

Antitrichomonal strains of Bacillus thuringiensis

  • Shigeo KondoAffiliated withDepartment of Parasitology, Aichi Medical University School of Medicine, Nagakute, Aichi, 480-1195, Japan
  • , Eiichi MizukiAffiliated withBiotechnology and Food Research Institute, Fukuoka Industrial Technology Centre, Kurume, Fukuoka, 839-0861, Japan
  • , Tetsuyuki AkaoAffiliated withBiotechnology and Food Research Institute, Fukuoka Industrial Technology Centre, Kurume, Fukuoka, 839-0861, Japan
  • , Michio OhbaAffiliated withBioresource and Management, Graduate School of Bioresource and Bio-environmental Sciences, Kyushu University, Fukuoka, 812-8581, Japan

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Abstract.

Parasporal inclusion proteins from a total of 816 Bacillus thuringiensis strains isolated in Japan were examined for antitrichomonal activity against Trichomonas vaginalis. Ten strains of B. thuringiensis inhibited the growth of T. vaginalis in 48 h cultures at 37°C. Moreover, the B622 and B626 strains clearly showed trichomonacidal effects against T. vaginalis. The H antigen serotypes of both strains were identified as H13/29 (pakistani/amagiensis). The parasporal inclusion protein from both strains consisted of three major polypeptides of 77, 45 and 25 kDa.