Journal of Cancer Research and Clinical Oncology

, Volume 134, Issue 10, pp 1067–1070

The role of omentectomy during the surgical staging in patients with clinical stage I endometrioid adenocarcinoma

Authors

    • Department of GynecologyAnkara Oncology Education and Research Hospital
  • Gülay Bilir Dilek
    • Department of PathologyAnkara Oncology Education and Research Hospital
Original Paper

DOI: 10.1007/s00432-008-0389-z

Cite this article as:
Metindir, J. & Dilek, G.B. J Cancer Res Clin Oncol (2008) 134: 1067. doi:10.1007/s00432-008-0389-z

Abstract

Objective

The aim of this study was to evaluate whether omentectomy should be a routine part of staging surgery in endometrioid adenocarcinoma.

Methods

A retrospective study was performed on 65 patients who were primarily treated by total abdominal hysterectomy, salpingo-oophorectomy, bilateral pelvic and para-aortic lymphadenectomy, infracolic omentectomy and peritoneal cytology for clinical stage I endometrial carcinoma between January 2002 and December 2005. Data on 65 patients who had been diagnosed with clinical stage I endometrial carcinoma were reviewed. Associations in the data obtained, pelvic and para-aortic lymph node status, depth of myometrial invasion, grade, vascular invasion, adnexal involvement, positive peritoneal cytology, lymph node metastasis, cervical stromal invasion, and tumor size, were investigated. The Chi-square (χ2) test was used for statistical analysis. Multivariate analysis was performed with logistic regression analyses.

Results

Four (6.2%) of 65 patients had omental metastasis, which was microscopic in two patients. As for extrauterine spread, the positivity rate of lymph node metastases was 10/65 (15.38%), peritoneal cytology was 7/65 (10.76%), and adnexal metastases was 10/65 (15.38%). Of those patients with omental metastasis, 2/10(20%) had positive nodes, 2/10(20%) had adnexal metastases, and 3/7(42.8%) had positive peritoneal cytologic findings. These four patients with omental metastasis had significantly higher rates of positive cytology (P = 0.003). Multivariate analysis revealed omental metastasis (P = 0.002; OR 46.5, CI 95% 3.899–554.575) to be significantly associated with positive peritoneal cytology

Conclusions

We conclude that despite the presence of normal-appearing omentum, omentectomy should be performed as a component of surgical staging in the presence of positive peritoneal cytology.

Keywords

Endometrioid adenocarcinoma Omentectomy Surgical staging

Copyright information

© Springer-Verlag 2008