Journal of Cancer Research and Clinical Oncology

, Volume 134, Issue 10, pp 1151–1153

Tamoxifen for salivary gland adenoid cystic carcinoma: report of two cases

Original Paper

DOI: 10.1007/s00432-008-0377-3

Cite this article as:
Elkin, A.D. & Jacobs, C.D. J Cancer Res Clin Oncol (2008) 134: 1151. doi:10.1007/s00432-008-0377-3

Abstract

Purpose

Adenoid cystic carcinoma of the salivary gland (ACC-SG) is a slow-growing tumor that is refractory to most chemotherapeutic agents. Estrogen receptor (ER) antagonists provide a novel approach for recurrent disease.

Methods

We report two cases of ACC-SC in which Tamoxifen/Toremifene were used.

Results

Both patients obtained long-term stability of disease with no associated toxicity.

Conclusions

Given the relatively unsuccessful treatments for ACC-SC and the low toxicity of ER antagonists, such therapy should be considered in these patients for its potential disease-stabilizing effects.

Keywords

Tamoxifen Salivary gland Adenoid cystic Estrogen receptor antagonist 

Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  1. 1.Department of MedicineStanford University School of MedicineStanfordUSA

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