European Journal of Pediatrics

, Volume 157, Issue 6, pp 479–481

Shift in antibiotic prescribing patterns in relation to antibiotic expenditure in paediatrics

  • M. A. van Houten
  • M. Laseur
  • J. L. L. Kimpen

DOI: 10.1007/s004310050858

Cite this article as:
van Houten, M., Laseur, M. & Kimpen, J. Eur J Pediatr (1998) 157: 479. doi:10.1007/s004310050858


In paediatrics, antibiotics are among the most commonly prescribed drugs. Because of an overall rise in health care costs, lack of uniformity in drug prescribing and the emergence of antibiotic resistance, monitoring and control of antibiotic use is of growing concern and strict antibiotic policies are warranted. Before such a policy can be implemented, detailed knowledge of antibiotic prescribing patterns and related costs is important. In this study a shift of antibiotic prescription patterns over time is described in relation to hospital antibiotic expenditure.

Conclusions A considerable shift in prescription patterns towards more expensive and broader spectrum antibiotics occurs in paediatrics, carrying a risk for the development of antibiotic resistance among the most prevalent micro-organisms in this age group.

Key words ChildrenAntibioticsDrug expenditureDrug utilizationPrescriptions

Copyright information

© Springer-Verlag Berlin Heidelberg 1998

Authors and Affiliations

  • M. A. van Houten
    • 1
  • M. Laseur
    • 3
  • J. L. L. Kimpen
    • 2
  1. 1.Beatrix Children's Hospital, University Hospital Groningen
  2. 2.University Children's Hospital “Het Wilhelmina Kinderziekenhuis”/AZU, P.O. Box 18009, 3501 CA Utrecht, The Netherlands, Tel. 31-30-2320911, Fax: 31-30-2330707NL
  3. 3.Department of Hospital Pharmacy, University Hospital Groningen, Groningen, The NetherlandsNL